Title |
What is the mechanism whereby cannabis use increases risk of psychosis?
|
---|---|
Published in |
Neurotoxicity Research, June 2008
|
DOI | 10.1007/bf03033802 |
Pubmed ID | |
Authors |
Sonija Luzi, Paul D. Morrison, John Powell, Marta Di Forti, Robin M. Murray |
Abstract |
Cannabis use has increased greatly over the last three decades. The various types of cannabis differ in their concentration of the main psychoactive component, Delta-9-tetrahydrocannabinol (THC), and the other major ingredient, cannabidiol (CBD). Plant engineering has maximized levels of THC, thus increasing the potency of street cannabis. It is well known that cannabis intoxication can cause brief psychotic symptoms like paranoia, whilst recent evidence demonstrates that heavy use of cannabis increases the risk of chronic psychoses like schizophrenia; genetic vulnerability seems to predispose some people to a higher risk. This paper starts to consider the neurochemical mechanisms whereby cannabis use increases the risk of psychosis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 3 | 43% |
Austria | 1 | 14% |
Unknown | 3 | 43% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 7 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 2% |
Brazil | 2 | 1% |
United Kingdom | 2 | 1% |
Hungary | 1 | <1% |
Italy | 1 | <1% |
Spain | 1 | <1% |
Canada | 1 | <1% |
Unknown | 127 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 33 | 24% |
Student > Ph. D. Student | 15 | 11% |
Student > Master | 14 | 10% |
Researcher | 13 | 9% |
Professor | 10 | 7% |
Other | 33 | 24% |
Unknown | 20 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 40 | 29% |
Agricultural and Biological Sciences | 21 | 15% |
Psychology | 20 | 14% |
Neuroscience | 10 | 7% |
Biochemistry, Genetics and Molecular Biology | 5 | 4% |
Other | 12 | 9% |
Unknown | 30 | 22% |