Title |
Ginger (Zingiber officinale) and chemotherapy-induced nausea and vomiting: a systematic literature review
|
---|---|
Published in |
Nutrition Reviews, March 2013
|
DOI | 10.1111/nure.12016 |
Pubmed ID | |
Authors |
Wolfgang M Marx, Laisa Teleni, Alexandra L McCarthy, Luis Vitetta, Dan McKavanagh, Damien Thomson, Elisabeth Isenring |
Abstract |
Chemotherapy-induced nausea and vomiting (CINV) is a common side-effect of cytotoxic treatment. It continues to affect a significant proportion of patients despite the widespread use of antiemetic medication. In traditional medicine, ginger (Zingiber officinale) has been used to prevent and treat nausea in many cultures for thousands of years. However, its use has not been confirmed in the chemotherapy context. To determine the potential use of ginger as a prophylactic or treatment for CINV, a systematic literature review was conducted. Reviewed studies comprised randomized controlled trials or crossover trials that investigated the anti-CINV effect of ginger as the sole independent variable in chemotherapy patients. Seven studies met the inclusion criteria. All studies were assessed on methodological quality and their limitations were identified. Studies were mixed in their support of ginger as an anti-CINV treatment in patients receiving chemotherapy, with three demonstrating a positive effect, two in favor but with caveats, and two showing no effect on measures of CINV. Future studies are required to address the limitations identified before clinical use can be recommended. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 5 | 38% |
United Kingdom | 2 | 15% |
Netherlands | 1 | 8% |
United States | 1 | 8% |
Canada | 1 | 8% |
France | 1 | 8% |
Ireland | 1 | 8% |
Unknown | 1 | 8% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 5 | 38% |
Members of the public | 4 | 31% |
Scientists | 3 | 23% |
Science communicators (journalists, bloggers, editors) | 1 | 8% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | <1% |
Australia | 2 | <1% |
Canada | 1 | <1% |
Unknown | 216 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 58 | 26% |
Student > Master | 28 | 13% |
Researcher | 20 | 9% |
Student > Ph. D. Student | 16 | 7% |
Student > Doctoral Student | 9 | 4% |
Other | 35 | 16% |
Unknown | 55 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 48 | 22% |
Nursing and Health Professions | 34 | 15% |
Agricultural and Biological Sciences | 28 | 13% |
Biochemistry, Genetics and Molecular Biology | 14 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 11 | 5% |
Other | 23 | 10% |
Unknown | 63 | 29% |