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Effect of Nanoparticle Stabilization and Physicochemical Properties on Exposure Outcome: Acute Toxicity of Silver Nanoparticle Preparations in Zebrafish (Danio rerio)

Overview of attention for article published in Environmental Science & Technology, March 2013
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4 X users

Citations

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53 Dimensions

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79 Mendeley
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Title
Effect of Nanoparticle Stabilization and Physicochemical Properties on Exposure Outcome: Acute Toxicity of Silver Nanoparticle Preparations in Zebrafish (Danio rerio)
Published in
Environmental Science & Technology, March 2013
DOI 10.1021/es303695f
Pubmed ID
Authors

Stephen Cunningham, Margaret E. Brennan-Fournet, Deirdre Ledwith, Lucy Byrnes, Lokesh Joshi

Abstract

Nanotechnology has vast potential for expanded development and novel application in numerous sectors of society. With growing use and applications, substantial production volumes and associated environmental release can be anticipated. Exposure effect of nanoparticles (NP) on biological systems may be intrinsic to their physicochemical properties introducing unknown associated risk. Herein, we expand the knowledge of health and environmental impact of silver nanoparticles (AgNPs), testing the acute toxicity of 14 AgNP preparations on developing zebrafish embryos (Danio rerio). Toxicological end points, including mortality, hatching rate, and heart rate were recorded. Concentration, stabilization agent and physicochemical properties were monitored as contributing outcome factors. Our findings indicate wide ranging LC50 24 h postfertilization values (0.487 ppm (0.315, 0.744 95% CI) to 47.89 ppm (18.45, 203.49 95% CI)), and indicate surface charge and ionic dissolution as key contributory factors in AgNP exposure outcome.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 3 4%
United States 1 1%
Portugal 1 1%
Unknown 74 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 22%
Student > Master 14 18%
Researcher 11 14%
Professor > Associate Professor 7 9%
Student > Bachelor 5 6%
Other 15 19%
Unknown 10 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 24%
Environmental Science 17 22%
Chemistry 9 11%
Medicine and Dentistry 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Other 14 18%
Unknown 13 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2014.
All research outputs
#15,740,505
of 25,377,790 outputs
Outputs from Environmental Science & Technology
#15,735
of 20,675 outputs
Outputs of similar age
#121,653
of 210,388 outputs
Outputs of similar age from Environmental Science & Technology
#160
of 245 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 20,675 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.8. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,388 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 245 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.