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The origin and evolution of cell types

Overview of attention for article published in Nature Reviews Genetics, November 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
177 X users
facebook
13 Facebook pages
wikipedia
3 Wikipedia pages
googleplus
5 Google+ users

Citations

dimensions_citation
585 Dimensions

Readers on

mendeley
1167 Mendeley
citeulike
9 CiteULike
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Title
The origin and evolution of cell types
Published in
Nature Reviews Genetics, November 2016
DOI 10.1038/nrg.2016.127
Pubmed ID
Authors

Detlev Arendt, Jacob M. Musser, Clare V. H. Baker, Aviv Bergman, Connie Cepko, Douglas H. Erwin, Mihaela Pavlicev, Gerhard Schlosser, Stefanie Widder, Manfred D. Laubichler, Günter P. Wagner

Abstract

Cell types are the basic building blocks of multicellular organisms and are extensively diversified in animals. Despite recent advances in characterizing cell types, classification schemes remain ambiguous. We propose an evolutionary definition of a cell type that allows cell types to be delineated and compared within and between species. Key to cell type identity are evolutionary changes in the 'core regulatory complex' (CoRC) of transcription factors, that make emergent sister cell types distinct, enable their independent evolution and regulate cell type-specific traits termed apomeres. We discuss the distinction between developmental and evolutionary lineages, and present a roadmap for future research.

X Demographics

X Demographics

The data shown below were collected from the profiles of 177 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 1,167 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 5 <1%
United States 4 <1%
Germany 3 <1%
Spain 2 <1%
Mexico 2 <1%
Italy 2 <1%
Uruguay 1 <1%
Australia 1 <1%
Brazil 1 <1%
Other 10 <1%
Unknown 1136 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 292 25%
Researcher 211 18%
Student > Bachelor 119 10%
Student > Master 110 9%
Student > Doctoral Student 53 5%
Other 187 16%
Unknown 195 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 352 30%
Biochemistry, Genetics and Molecular Biology 340 29%
Neuroscience 94 8%
Medicine and Dentistry 40 3%
Computer Science 18 2%
Other 96 8%
Unknown 227 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 118. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 November 2023.
All research outputs
#361,593
of 25,728,855 outputs
Outputs from Nature Reviews Genetics
#175
of 2,746 outputs
Outputs of similar age
#6,875
of 319,549 outputs
Outputs of similar age from Nature Reviews Genetics
#6
of 36 outputs
Altmetric has tracked 25,728,855 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,746 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 32.5. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,549 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.