| Title |
The variant histone H2A.V of Drosophila—three roles, two guises
|
|---|---|
| Published in |
Chromosoma, April 2013
|
| DOI | 10.1007/s00412-013-0409-x |
| Pubmed ID | |
| Authors |
Sandro Baldi, Peter B. Becker |
| Abstract |
Histone variants play important roles in eukaryotic genome organization, the control of gene expression, cell division and DNA repair. Unlike other organisms that employ several H2A variants for different functions, the parsimonious fruit fly Drosophila melanogaster gets along with just a single H2A variant, H2A.V. Remarkably, H2A.V unites within one molecule features and functions of two different mammalian H2A variants, H2A.Z and H2A.X. Accordingly, H2A.V is involved in diverse functions, as an element of a class of active promoter structure, as a foundation for heterochromatin assembly and as a DNA damage sensor. Here, we comprehensively review the current knowledge of this fascinating histone variant. |
Mendeley readers
The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 89 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 22 | 25% |
| Researcher | 14 | 16% |
| Student > Master | 10 | 11% |
| Student > Bachelor | 7 | 8% |
| Student > Doctoral Student | 6 | 7% |
| Other | 13 | 15% |
| Unknown | 17 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 40 | 45% |
| Agricultural and Biological Sciences | 26 | 29% |
| Unspecified | 3 | 3% |
| Medicine and Dentistry | 1 | 1% |
| Chemistry | 1 | 1% |
| Other | 2 | 2% |
| Unknown | 16 | 18% |