Title |
Chronic cranberry juice consumption restores cholesterol profiles and improves endothelial function in ovariectomized rats
|
---|---|
Published in |
European Journal of Nutrition, July 2012
|
DOI | 10.1007/s00394-012-0425-2 |
Pubmed ID | |
Authors |
Lai-Ming Yung, Xiao Yu Tian, Wing Tak Wong, Fung Ping Leung, Lai Hang Yung, Zhen Yu Chen, Chi Wai Lau, Paul M. Vanhoutte, Xiaoqiang Yao, Yu Huang |
Abstract |
Postmenopausal women experience higher risks for cardiovascular diseases than age-matched men and pre-menopausal women. There is a need for better treatment strategy for estrogen-deficient-related cardiovascular complications. We and others have recently reported that activated renin-angiotensin system and the associated oxidative stress impaired endothelium-dependent relaxation in ovariectomized rat, while angiotensin receptor blocker rescues endothelial dysfunction. Dietary supplements and lifestyle modifications provide an alternative way to improve cardiovascular health. The present study tests the hypothesis that chronic cranberry juice consumption improves cholesterol profiles and vascular functions in estrogen-deficient animal model. The effect of cranberry consumption on expression and activity of renin-angiotensin system in the vasculature will be determined. |
X Demographics
Geographical breakdown
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Canada | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 142 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 72 | 51% |
Student > Ph. D. Student | 10 | 7% |
Student > Master | 6 | 4% |
Researcher | 4 | 3% |
Student > Postgraduate | 3 | 2% |
Other | 7 | 5% |
Unknown | 40 | 28% |
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Chemistry | 7 | 5% |
Other | 25 | 18% |
Unknown | 42 | 30% |