| Title |
Molecular Communication from Skeletal Muscle to Bone: A Review for Muscle-Derived Myokines Regulating Bone Metabolism
|
|---|---|
| Published in |
Calcified Tissue International, November 2016
|
| DOI | 10.1007/s00223-016-0209-4 |
| Pubmed ID | |
| Authors |
Baosheng Guo, Zong-Kang Zhang, Chao Liang, Jie Li, Jin Liu, Aiping Lu, Bao-Ting Zhang, Ge Zhang |
| Abstract |
Besides the mechanical loading-dependent paradigm, skeletal muscle also serves as an endocrine organ capable of secreting cytokines to modulate bone metabolism. In this review, we focused on reviewing the myokines involved in communication from skeletal muscle to bone, i.e. (1) myostatin and myostatin-binding proteins including follistatin and decorin, (2) interleukins including interleukin-6 (IL-6), interleukin-7 (IL-7) and interleukin-15 (IL-15), (3) insulin-like growth factor 1 (IGF-1) and its binding proteins, (4) other myokines including PGC-1α-irisin system and osteoglycin (OGN). To better understand the molecular communication from skeletal muscle to bone, we have summarized the recent advances in muscle-derived cytokines regulating bone metabolism in this review. |
X Demographics
The data shown below were collected from the profiles of 36 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 11% |
| Spain | 2 | 6% |
| United Kingdom | 2 | 6% |
| Brazil | 1 | 3% |
| Argentina | 1 | 3% |
| Peru | 1 | 3% |
| Puerto Rico | 1 | 3% |
| Pakistan | 1 | 3% |
| Mexico | 1 | 3% |
| Other | 8 | 22% |
| Unknown | 14 | 39% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 25 | 69% |
| Scientists | 10 | 28% |
| Practitioners (doctors, other healthcare professionals) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 101 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| Australia | 1 | <1% |
| Unknown | 99 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 14 | 14% |
| Student > Ph. D. Student | 12 | 12% |
| Student > Doctoral Student | 10 | 10% |
| Student > Master | 10 | 10% |
| Researcher | 8 | 8% |
| Other | 22 | 22% |
| Unknown | 25 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 22% |
| Biochemistry, Genetics and Molecular Biology | 19 | 19% |
| Sports and Recreations | 9 | 9% |
| Agricultural and Biological Sciences | 9 | 9% |
| Nursing and Health Professions | 4 | 4% |
| Other | 9 | 9% |
| Unknown | 29 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 November 2021.
All research outputs
#1,668,798
of 22,899,952 outputs
Outputs from Calcified Tissue International
#112
of 1,760 outputs
Outputs of similar age
#32,184
of 313,008 outputs
Outputs of similar age from Calcified Tissue International
#2
of 19 outputs
Altmetric has tracked 22,899,952 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,760 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,008 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.