Title |
Evaluation of a Records-Review Surveillance System Used to Determine the Prevalence of Autism Spectrum Disorders
|
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Published in |
Journal of Autism and Developmental Disorders, June 2010
|
DOI | 10.1007/s10803-010-1050-7 |
Pubmed ID | |
Authors |
Rachel Nonkin Avchen, Lisa D. Wiggins, Owen Devine, Kim Van Naarden Braun, Catherine Rice, Nancy C. Hobson, Diana Schendel, Marshalyn Yeargin-Allsopp |
Abstract |
We conducted the first study that estimates the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of a population-based autism spectrum disorders (ASD) surveillance system developed at the Centers for Disease Control and Prevention. The system employs a records-review methodology that yields ASD classification (case versus non-ASD case) and was compared with classification based on clinical examination. The study enrolled 177 children. Estimated specificity (0.96, [CI(.95) = 0.94, 0.99]), PPV (0.79 [CI(.95) = 0.66, 0.93]), and NPV (0.91 [CI(.95) = 0.87, 0.96]) were high. Sensitivity was lower (0.60 [CI(.95) = 0.45, 0.75]). Given diagnostic heterogeneity, and the broad array of ASD in the population, identifying children with ASD is challenging. Records-based surveillance yields a population-based estimate of ASD that is likely conservative. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 1% |
Unknown | 71 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 14% |
Student > Ph. D. Student | 10 | 14% |
Student > Master | 9 | 13% |
Student > Bachelor | 7 | 10% |
Student > Doctoral Student | 6 | 8% |
Other | 15 | 21% |
Unknown | 15 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 19 | 26% |
Social Sciences | 12 | 17% |
Medicine and Dentistry | 11 | 15% |
Agricultural and Biological Sciences | 3 | 4% |
Arts and Humanities | 3 | 4% |
Other | 6 | 8% |
Unknown | 18 | 25% |