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Predicted Enhanced Human Propensity of Current Avian-Like H1N1 Swine Influenza Virus from China

Overview of attention for article published in PLOS ONE, November 2016
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Title
Predicted Enhanced Human Propensity of Current Avian-Like H1N1 Swine Influenza Virus from China
Published in
PLOS ONE, November 2016
DOI 10.1371/journal.pone.0165451
Pubmed ID
Authors

Veljko Veljkovic, Nevena Veljkovic, Slobodan Paessler, Marco Goeijenbier, Vladimir Perovic, Sanja Glisic, Claude P. Muller

Abstract

Influenza A virus (IAV) subtypes against which little or no pre-existing immunity exists in humans represent a serious threat to global public health. Monitoring of IAV in animal hosts is essential for early and rapid detection of potential pandemic IAV strains to prevent their spread. Recently, the increased pandemic potential of the avian-like swine H1N1 IAV A/swine/Guangdong/104/2013 has been suggested. The virus is infectious in humans and the general population seems to lack neutralizing antibodies against this virus. Here we present an in silico analysis that shows a strong human propensity of this swine virus further confirming its pandemic potential. We suggest mutations which would further enhance its human propensity. We also propose conserved antigenic determinants which could serve as a component of a prepandemic vaccine. The bioinformatics tool, which can be used to further monitor the evolution of swine influenza viruses towards a pandemic virus, are described here and are made publically available (http://www.vin.bg.ac.rs/180/tools/iav_mon.php; http://www.biomedprotection.com/iav_mon.php).

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 32%
Student > Doctoral Student 2 11%
Student > Bachelor 2 11%
Student > Ph. D. Student 2 11%
Other 1 5%
Other 2 11%
Unknown 4 21%
Readers by discipline Count As %
Medicine and Dentistry 4 21%
Biochemistry, Genetics and Molecular Biology 2 11%
Agricultural and Biological Sciences 2 11%
Nursing and Health Professions 1 5%
Earth and Planetary Sciences 1 5%
Other 1 5%
Unknown 8 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 December 2017.
All research outputs
#14,869,124
of 22,899,952 outputs
Outputs from PLOS ONE
#124,402
of 195,237 outputs
Outputs of similar age
#188,250
of 313,008 outputs
Outputs of similar age from PLOS ONE
#2,402
of 3,995 outputs
Altmetric has tracked 22,899,952 research outputs across all sources so far. This one is in the 33rd percentile – i.e., 33% of other outputs scored the same or lower than it.
So far Altmetric has tracked 195,237 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.1. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,008 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3,995 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.