Title |
New insights into symptoms and neurocircuit function of anorexia nervosa
|
---|---|
Published in |
Nature Reviews Neuroscience, July 2009
|
DOI | 10.1038/nrn2682 |
Pubmed ID | |
Authors |
Walter H. Kaye, Julie L. Fudge, Martin Paulus |
Abstract |
Individuals with anorexia nervosa have a relentless preoccupation with dieting and weight loss that results in severe emaciation and sometimes death. It is controversial whether such symptoms are secondary to psychosocial influences, are a consequence of obsessions and anxiety or reflect a primary disturbance of brain appetitive circuits. New brain imaging technology provides insights into ventral and dorsal neural circuit dysfunction - perhaps related to altered serotonin and dopamine metabolism - that contributes to the puzzling symptoms found in people with eating disorders. For example, altered insula activity could explain interoceptive dysfunction, and altered striatal activity might shed light on altered reward modulation in people with anorexia nervosa. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 40% |
Unknown | 3 | 60% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 2 | 40% |
Members of the public | 2 | 40% |
Scientists | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 6 | <1% |
Spain | 4 | <1% |
United Kingdom | 4 | <1% |
Netherlands | 3 | <1% |
Germany | 3 | <1% |
Brazil | 2 | <1% |
Poland | 2 | <1% |
Canada | 2 | <1% |
Austria | 1 | <1% |
Other | 7 | <1% |
Unknown | 850 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 152 | 17% |
Student > Ph. D. Student | 123 | 14% |
Researcher | 118 | 13% |
Student > Master | 116 | 13% |
Student > Doctoral Student | 57 | 6% |
Other | 165 | 19% |
Unknown | 153 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 254 | 29% |
Medicine and Dentistry | 146 | 17% |
Agricultural and Biological Sciences | 105 | 12% |
Neuroscience | 95 | 11% |
Nursing and Health Professions | 27 | 3% |
Other | 72 | 8% |
Unknown | 185 | 21% |