Title |
Semi-autonomous inline water analyzer: design of a common light detector for bacterial, phage, and immunological biosensors
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Published in |
Environmental Science and Pollution Research, November 2016
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DOI | 10.1007/s11356-016-8010-5 |
Pubmed ID | |
Authors |
Elodie C.T. Descamps, Damien Meunier, Catherine Brutesco, Sandra Prévéral, Nathalie Franche, Ingrid Bazin, Bertrand Miclot, Philippe Larosa, Camille Escoffier, Jean-Raphael Fantino, Daniel Garcia, Mireille Ansaldi, Agnès Rodrigue, David Pignol, Pierre Cholat, Nicolas Ginet |
Abstract |
The use of biosensors as sensitive and rapid alert systems is a promising perspective to monitor accidental or intentional environmental pollution, but their implementation in the field is limited by the lack of adapted inline water monitoring devices. We describe here the design and initial qualification of an analyzer prototype able to accommodate three types of biosensors based on entirely different methodologies (immunological, whole-cell, and bacteriophage biosensors), but whose responses rely on the emission of light. We developed a custom light detector and a reaction chamber compatible with the specificities of the three systems and resulting in statutory detection limits. The water analyzer prototype resulting from the COMBITOX project can be situated at level 4 on the Technology Readiness Level (TRL) scale and this technical advance paves the way to the use of biosensors on-site. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 7 | 33% |
Student > Master | 5 | 24% |
Student > Bachelor | 2 | 10% |
Professor | 1 | 5% |
Researcher | 1 | 5% |
Other | 1 | 5% |
Unknown | 4 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 5 | 24% |
Agricultural and Biological Sciences | 4 | 19% |
Chemical Engineering | 1 | 5% |
Veterinary Science and Veterinary Medicine | 1 | 5% |
Immunology and Microbiology | 1 | 5% |
Other | 4 | 19% |
Unknown | 5 | 24% |