Title |
Variants in the ATP-Binding Cassette Transporter (ABCA7), Apolipoprotein E ϵ4, and the Risk of Late-Onset Alzheimer Disease in African Americans
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Published in |
JAMA: Journal of the American Medical Association, April 2013
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DOI | 10.1001/jama.2013.2973 |
Pubmed ID | |
Authors |
Christiane Reitz, Gyungah Jun, Adam Naj, Ruchita Rajbhandary, Badri Narayan Vardarajan, Li-San Wang, Otto Valladares, Chiao-Feng Lin, Eric B. Larson, Neill R. Graff-Radford, Denis Evans, Philip L. De Jager, Paul K. Crane, Joseph D. Buxbaum, Jill R. Murrell, Towfique Raj, Nilufer Ertekin-Taner, Mark Logue, Clinton T. Baldwin, Robert C. Green, Lisa L. Barnes, Laura B. Cantwell, M. Daniele Fallin, Rodney C. P. Go, Patrick Griffith, Thomas O. Obisesan, Jennifer J. Manly, Kathryn L. Lunetta, M. Ilyas Kamboh, Oscar L. Lopez, David A. Bennett, Hugh Hendrie, Kathleen S. Hall, Alison M. Goate, Goldie S. Byrd, Walter A. Kukull, Tatiana M. Foroud, Jonathan L. Haines, Lindsay A. Farrer, Margaret A. Pericak-Vance, Gerard D. Schellenberg, Richard Mayeux, for the Alzheimer Disease Genetics Consortium |
Abstract |
Genetic variants associated with susceptibility to late-onset Alzheimer disease are known for individuals of European ancestry, but whether the same or different variants account for the genetic risk of Alzheimer disease in African American individuals is unknown. Identification of disease-associated variants helps identify targets for genetic testing, prevention, and treatment. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 13% |
Netherlands | 1 | 13% |
Unknown | 6 | 75% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 75% |
Scientists | 1 | 13% |
Practitioners (doctors, other healthcare professionals) | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 1% |
France | 1 | <1% |
Brazil | 1 | <1% |
Canada | 1 | <1% |
United Kingdom | 1 | <1% |
Japan | 1 | <1% |
Spain | 1 | <1% |
Unknown | 302 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 60 | 19% |
Student > Ph. D. Student | 47 | 15% |
Student > Master | 36 | 12% |
Student > Bachelor | 24 | 8% |
Other | 24 | 8% |
Other | 60 | 19% |
Unknown | 61 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 73 | 23% |
Medicine and Dentistry | 44 | 14% |
Biochemistry, Genetics and Molecular Biology | 39 | 13% |
Neuroscience | 38 | 12% |
Psychology | 11 | 4% |
Other | 34 | 11% |
Unknown | 73 | 23% |