↓ Skip to main content

Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2

Overview of attention for article published in Nature Genetics, August 2010
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

Mentioned by

blogs
2 blogs
wikipedia
2 Wikipedia pages

Citations

dimensions_citation
322 Dimensions

Readers on

mendeley
286 Mendeley
citeulike
3 CiteULike
connotea
1 Connotea
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2
Published in
Nature Genetics, August 2010
DOI 10.1038/ng.639
Pubmed ID
Authors

Thorsten Thye, Fredrik O Vannberg, Sunny H Wong, Ellis Owusu-Dabo, Ivy Osei, John Gyapong, Giorgio Sirugo, Fatou Sisay-Joof, Anthony Enimil, Margaret A Chinbuah, Sian Floyd, David K Warndorff, Lifted Sichali, Simon Malema, Amelia C Crampin, Bagrey Ngwira, Yik Y Teo, Kerrin Small, Kirk Rockett, Dominic Kwiatkowski, Paul E Fine, Philip C Hill, Melanie Newport, Christian Lienhardt, Richard A Adegbola, Tumani Corrah, Andreas Ziegler, Andrew P Morris, Christian G Meyer, Rolf D Horstmann, Adrian V S Hill

Abstract

We combined two tuberculosis genome-wide association studies from Ghana and The Gambia with subsequent replication in a combined 11,425 individuals. rs4331426, located in a gene-poor region on chromosome 18q11.2, was associated with disease (combined P = 6.8 x 10(-9), odds ratio = 1.19, 95% CI = 1.13-1.27). Our study demonstrates that genome-wide association studies can identify new susceptibility loci for infectious diseases, even in African populations, in which levels of linkage disequilibrium are particularly low.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 286 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 4 1%
United States 3 1%
South Africa 2 <1%
United Kingdom 2 <1%
Spain 2 <1%
Thailand 1 <1%
Switzerland 1 <1%
Japan 1 <1%
Finland 1 <1%
Other 0 0%
Unknown 269 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 59 21%
Researcher 57 20%
Student > Master 30 10%
Student > Bachelor 23 8%
Professor 22 8%
Other 60 21%
Unknown 35 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 91 32%
Medicine and Dentistry 57 20%
Biochemistry, Genetics and Molecular Biology 45 16%
Immunology and Microbiology 17 6%
Social Sciences 6 2%
Other 24 8%
Unknown 46 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 May 2016.
All research outputs
#2,110,860
of 26,017,215 outputs
Outputs from Nature Genetics
#2,791
of 7,655 outputs
Outputs of similar age
#7,505
of 108,724 outputs
Outputs of similar age from Nature Genetics
#16
of 50 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,655 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.8. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 108,724 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.