| Title |
Effects of Low Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) on Gamma Frequency Oscillations and Event-Related Potentials During Processing of Illusory Figures in Autism
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, November 2008
|
| DOI | 10.1007/s10803-008-0662-7 |
| Pubmed ID | |
| Authors |
Estate M. Sokhadze, Ayman El-Baz, Joshua Baruth, Grace Mathai, Lonnie Sears, Manuel F. Casanova |
| Abstract |
Previous studies by our group suggest that the neuropathology of autism is characterized by a disturbance of cortical modularity. In this model a decrease in the peripheral neuropil space of affected minicolumns provides for an inhibitory deficit and a readjustment in their signal to noise bias during information processing. In this study we proposed using low frequency transcranial magnetic stimulation (rTMS) as a way increasing the surround inhibition of minicolumns in autism. Thirteen patients (ADOS and ADI-R diagnosed) and equal number of controls participated in the study. Repetitive TMS was delivered at 0.5 Hz, 2 times per week for 3 weeks. Outcome measures based on event-related potentials (ERP), induced gamma activity, and behavioral measures showed significant post-TMS improvement. The results suggest that rTMS offers a potential therapeutic intervention for autism. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 186 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 2% |
| Canada | 2 | 1% |
| Norway | 1 | <1% |
| Switzerland | 1 | <1% |
| United Kingdom | 1 | <1% |
| Unknown | 177 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 13% |
| Researcher | 23 | 12% |
| Student > Master | 23 | 12% |
| Professor | 15 | 8% |
| Student > Doctoral Student | 14 | 8% |
| Other | 50 | 27% |
| Unknown | 36 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 55 | 30% |
| Medicine and Dentistry | 30 | 16% |
| Neuroscience | 23 | 12% |
| Agricultural and Biological Sciences | 12 | 6% |
| Nursing and Health Professions | 5 | 3% |
| Other | 18 | 10% |
| Unknown | 43 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 May 2013.
All research outputs
#4,035,805
of 23,867,274 outputs
Outputs from Journal of Autism and Developmental Disorders
#1,684
of 5,240 outputs
Outputs of similar age
#21,835
of 171,473 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#5
of 12 outputs
Altmetric has tracked 23,867,274 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,240 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 171,473 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.