| Title |
The effects of kappa-opioid receptor ligands on prepulse inhibition and CRF-induced prepulse inhibition deficits in the rat
|
|---|---|
| Published in |
Psychopharmacology, March 2010
|
| DOI | 10.1007/s00213-010-1799-6 |
| Pubmed ID | |
| Authors |
Hugo A. Tejeda, Vladimir I. Chefer, Agustin Zapata, Toni S. Shippenberg |
| Abstract |
Kappa-opioid receptor (KOR) agonists produce dysphoria and psychotomimesis in humans. KORs are enriched in the prefrontal cortex and other brain regions that regulate mood and cognitive function. Dysregulation of the dynorphin/KOR system has been implicated in the pathogenesis of schizophrenia, depression, and bipolar disorder. Prepulse inhibition of the acoustic startle reflex (PPI), a sensorimotor gating process, is disrupted in many psychiatric disorders. |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 40 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 24% |
| Researcher | 6 | 15% |
| Student > Master | 6 | 15% |
| Student > Bachelor | 5 | 12% |
| Student > Doctoral Student | 3 | 7% |
| Other | 6 | 15% |
| Unknown | 5 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 9 | 22% |
| Agricultural and Biological Sciences | 8 | 20% |
| Medicine and Dentistry | 7 | 17% |
| Neuroscience | 6 | 15% |
| Biochemistry, Genetics and Molecular Biology | 2 | 5% |
| Other | 3 | 7% |
| Unknown | 6 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2013.
All research outputs
#15,270,134
of 22,707,247 outputs
Outputs from Psychopharmacology
#4,237
of 5,335 outputs
Outputs of similar age
#76,831
of 94,145 outputs
Outputs of similar age from Psychopharmacology
#35
of 41 outputs
Altmetric has tracked 22,707,247 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,335 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
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We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.