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Smelling the roses and seeing the light: gene therapy for ciliopathies

Overview of attention for article published in Trends in Biotechnology, April 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)

Mentioned by

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7 X users

Citations

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33 Dimensions

Readers on

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83 Mendeley
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Title
Smelling the roses and seeing the light: gene therapy for ciliopathies
Published in
Trends in Biotechnology, April 2013
DOI 10.1016/j.tibtech.2013.03.005
Pubmed ID
Authors

Jeremy C. McIntyre, Corey L. Williams, Jeffrey R. Martens

Abstract

Alterations in cilia formation or function underlie a growing class of pleiotropic disorders termed ciliopathies. The genetic basis of ciliopathies is remarkably complex, with an incomplete but expanding list of more than 89 loci implicated in various disorders. Current treatment of ciliopathies is limited to symptomatic therapy. However, our growing understanding of ciliopathy genetics, coupled with recent advances in gene delivery and endogenous gene and transcript repair demonstrated thus far in tissues of the eye, nose, and airway, offers hope for curative measures in the near future. This review highlights these advances, as well as the challenges that remain with the development of personalized medicine for treating a very complex spectrum of disease, penetrant in a variety of organ systems.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
United Kingdom 1 1%
Germany 1 1%
France 1 1%
Unknown 78 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 24 29%
Student > Ph. D. Student 20 24%
Student > Bachelor 10 12%
Student > Master 6 7%
Other 5 6%
Other 12 14%
Unknown 6 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 31 37%
Biochemistry, Genetics and Molecular Biology 18 22%
Neuroscience 12 14%
Medicine and Dentistry 9 11%
Business, Management and Accounting 1 1%
Other 5 6%
Unknown 7 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2014.
All research outputs
#7,263,349
of 25,371,288 outputs
Outputs from Trends in Biotechnology
#1,596
of 2,856 outputs
Outputs of similar age
#58,651
of 209,583 outputs
Outputs of similar age from Trends in Biotechnology
#14
of 20 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 2,856 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.5. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 209,583 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.