| Title |
Do Statins Cause Diabetes?
|
|---|---|
| Published in |
Current Diabetes Reports, March 2013
|
| DOI | 10.1007/s11892-013-0368-x |
| Pubmed ID | |
| Authors |
Mark R. Goldstein, Luca Mascitelli |
| Abstract |
A wealth of evidence has established that cholesterol-lowering statin drugs, widely used for the prevention of cardiovascular disease, do increase the risk of new-onset diabetes, possibly by impairing pancreatic beta cell function and decreasing peripheral insulin sensitivity. Groups at particular risk include the elderly, women, and Asians. The diabetogenic effect of statins appear directly related to statin dose and the degree of attained cholesterol lowering. Statins can cause hyperinsulinemia even in the absence of hyperglycemia and the potential mitogenic effects and implications of prolonged hyperinsulinemia are discussed. Suggestions are made as to how physicians might avert the hyperinsulinemic and diabetogenic effects of statin therapy in clinical practice, and modulate the detrimental effects of these drugs on exercise performance. Finally, long-term studies are needed to determine if the deleterious hyperinsulinemic and diabetogenic effects of statin therapy undermine the beneficial cardiovascular disease risk outcomes in various segments of the population. |
X Demographics
The data shown below were collected from the profiles of 39 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 13 | 33% |
| United States | 5 | 13% |
| South Africa | 2 | 5% |
| Korea, Democratic People's Republic of | 1 | 3% |
| Canada | 1 | 3% |
| Portugal | 1 | 3% |
| United Kingdom | 1 | 3% |
| Unknown | 15 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 26 | 67% |
| Practitioners (doctors, other healthcare professionals) | 9 | 23% |
| Scientists | 4 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| Mexico | 1 | 1% |
| Denmark | 1 | 1% |
| South Africa | 1 | 1% |
| Unknown | 79 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 14 | 17% |
| Student > Bachelor | 13 | 16% |
| Researcher | 9 | 11% |
| Student > Ph. D. Student | 9 | 11% |
| Student > Postgraduate | 5 | 6% |
| Other | 19 | 23% |
| Unknown | 14 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 28 | 34% |
| Pharmacology, Toxicology and Pharmaceutical Science | 11 | 13% |
| Nursing and Health Professions | 4 | 5% |
| Agricultural and Biological Sciences | 3 | 4% |
| Biochemistry, Genetics and Molecular Biology | 3 | 4% |
| Other | 13 | 16% |
| Unknown | 21 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 34. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 July 2023.
All research outputs
#1,122,256
of 24,451,065 outputs
Outputs from Current Diabetes Reports
#51
of 1,040 outputs
Outputs of similar age
#8,160
of 197,849 outputs
Outputs of similar age from Current Diabetes Reports
#3
of 13 outputs
Altmetric has tracked 24,451,065 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,040 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 197,849 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.