Title |
Design rules for nanomedical engineering: from physical virology to the applications of virus-based materials in medicine
|
---|---|
Published in |
Journal of Biological Physics, April 2013
|
DOI | 10.1007/s10867-013-9314-z |
Pubmed ID | |
Authors |
Amy M. Wen, Pooja H. Rambhia, Roger H. French, Nicole F. Steinmetz |
Abstract |
Physical virology seeks to define the principles of physics underlying viral infections, traditionally focusing on the fundamental processes governing virus assembly, maturation, and disassembly. A detailed understanding of virus structure and assembly has facilitated the development and analysis of virus-based materials for medical applications. In this Physical Virology review article, we discuss the recent developments in nanomedicine that help us to understand how physical properties affect the in vivo fate and clinical impact of (virus-based) nanoparticles. We summarize and discuss the design rules that need to be considered for the successful development and translation of virus-based nanomaterials from bench to bedside. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 40% |
Unknown | 3 | 60% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 4 | 80% |
Members of the public | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 3% |
Denmark | 1 | 1% |
China | 1 | 1% |
France | 1 | 1% |
Unknown | 71 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 23 | 30% |
Researcher | 11 | 14% |
Student > Master | 10 | 13% |
Student > Doctoral Student | 6 | 8% |
Student > Bachelor | 6 | 8% |
Other | 9 | 12% |
Unknown | 11 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 14 | 18% |
Agricultural and Biological Sciences | 11 | 14% |
Biochemistry, Genetics and Molecular Biology | 10 | 13% |
Engineering | 9 | 12% |
Physics and Astronomy | 5 | 7% |
Other | 14 | 18% |
Unknown | 13 | 17% |