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Implementation of a multidisciplinary pharmacogenomics clinic in a community health system

Overview of attention for article published in American Journal of Health-System Pharmacy, December 2016
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Title
Implementation of a multidisciplinary pharmacogenomics clinic in a community health system
Published in
American Journal of Health-System Pharmacy, December 2016
DOI 10.2146/ajhp160072
Pubmed ID
Authors

Henry M. Dunnenberger, Matthew Biszewski, Gillian C. Bell, Annette Sereika, Holley May, Samuel G. Johnson, Peter J. Hulick, Janardan Khandekar

Abstract

The development and implementation of a multidisciplinary pharmacogenomics clinic within the framework of an established community-based medical genetics program are described. Pharmacogenomics is an important component of precision medicine that holds considerable promise for pharmacotherapy optimization. As part of the development of a health system-wide integrated pharmacogenomics program, in early 2015 Northshore University Health-System established a pharmacogenomics clinic run by a multidisciplinary team including a medical geneticist, a pharmacist, a nurse practitioner, and genetic counselors. The team identified five key program elements: (1) a billable-service provider, (2) a process for documentation of relevant medication and family histories, (3) personnel with the knowledge required to interpret pharmacogenomic results, (4) personnel to discuss risks, benefits, and limitations of pharmacogenomic testing, and (5) a mechanism for reporting results. The most important program component is expert interpretation of genetic test results to provide clinically useful information; pharmacists are well positioned to provide that expertise. At the Northshore University HealthSystem pharmacogenomics clinic, patient encounters typically entail two one-hour visits and follow a standardized workflow. At the first visit, pharmacogenomics-focused medication and family histories are obtained, risks and benefits of genetic testing are explained, and a test sample is collected; at the second visit, test results are provided along with evidence-based pharmacotherapy recommendations. A multidisciplinary clinic providing genotyping and related services can facilitate the integration of pharmacogenomics into clinical care and meet the needs of early adopters of precision medicine.

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Mendeley readers

Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 99 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 14%
Student > Master 13 13%
Student > Bachelor 12 12%
Researcher 9 9%
Student > Doctoral Student 7 7%
Other 18 18%
Unknown 26 26%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 28 28%
Medicine and Dentistry 17 17%
Nursing and Health Professions 6 6%
Agricultural and Biological Sciences 4 4%
Biochemistry, Genetics and Molecular Biology 4 4%
Other 13 13%
Unknown 27 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 November 2016.
All research outputs
#18,483,671
of 22,903,988 outputs
Outputs from American Journal of Health-System Pharmacy
#3,047
of 3,628 outputs
Outputs of similar age
#304,674
of 416,461 outputs
Outputs of similar age from American Journal of Health-System Pharmacy
#59
of 67 outputs
Altmetric has tracked 22,903,988 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,628 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one is in the 3rd percentile – i.e., 3% of its peers scored the same or lower than it.
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We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.