Chapter title |
Utility of Insects for Studying Human Pathogens and Evaluating New Antimicrobial Agents.
|
---|---|
Chapter number | 194 |
Book title |
Yellow Biotechnology I
|
Published in |
Advances in biochemical engineering biotechnology, April 2013
|
DOI | 10.1007/10_2013_194 |
Pubmed ID | |
Book ISBNs |
978-3-64-239862-9, 978-3-64-239863-6
|
Authors |
Wang Y, Li DD, Jiang YY, Mylonakis E, Yan Wang, De-Dong Li, Yuan-Ying Jiang, Eleftherios Mylonakis, Wang, Yan, Li, De-Dong, Jiang, Yuan-Ying, Mylonakis, Eleftherios |
Abstract |
Insect models, such as Galleria mellonella and Drosophila melanogaster have significant ethical, logistical, and economic advantages over mammalian models for the studies of infectious diseases. Using these models, various pathogenic microbes have been studied and many novel virulence genes have been identified. Notably, because insects are susceptible to a wide variety of human pathogens and have immune responses similar to those of mammals, they offer the opportunity to understand innate immune responses against human pathogens better. It is important to note that insect pathosystems have also offered a simple strategy to evaluate the efficacy and toxicity of many antimicrobial agents. Overall, insect models provide a rapid, inexpensive, and reliable way as complementary hosts to conventional vertebrate animal models to study pathogenesis and antimicrobial agents. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 2 | 13% |
Unknown | 14 | 88% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 4 | 25% |
Student > Ph. D. Student | 3 | 19% |
Researcher | 2 | 13% |
Student > Doctoral Student | 1 | 6% |
Student > Master | 1 | 6% |
Other | 1 | 6% |
Unknown | 4 | 25% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 4 | 25% |
Biochemistry, Genetics and Molecular Biology | 3 | 19% |
Linguistics | 1 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 6% |
Nursing and Health Professions | 1 | 6% |
Other | 1 | 6% |
Unknown | 5 | 31% |