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Attention Score in Context
| Title |
Immunochromatographic determination of bacopaside I in biological samples
|
|---|---|
| Published in |
Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences, November 2016
|
| DOI | 10.1016/j.jchromb.2016.11.022 |
| Pubmed ID | |
| Authors |
Sontaya Sookying, Dumrongsak Pekthong, Sarawut Oo-puthinan, Watoo Phrompittayarat, Waraporn Putalun, Hiroyuki Tanaka, Jie Xing, Zhaoqi Zhan, Nantaka Khorana, Nitra Nuengchamnong, Kornkanok Ingkaninan |
| Abstract |
We describe a novel immunochromatographic method for qualitative and quantitative analyses of bacopaside I, a bioactive constituent in Bacopa monnieri (L.) Wettst in biological samples. The assay was performed on polyethersulfone membrane using a polyclonal antibody raised against bacopaside I. The finalised method could quantitatively determine bacopaside I in the range of 31.3-1000.0ng and the detection and quantification limits were 1.0 and 31.3ng, respectively. The percentage recoveries of bacopaside I in blood and urine were nearly 100% indicating the accuracy of the extraction. The method was then applied for the determination of this compound in rat serum, urine and feces after an oral dose of 15mg/kg body weight. About 4% of the ingested dose of bacopaside I was detected in rat feces but none was detected in serum and urine which accorded with results from liquid chromatography tandem mass spectrometry. The accuracy, selectivity, sensitivity of the method are appropriate for in vivo pharmacokinetic studies. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 6 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 2 | 33% |
| Unspecified | 1 | 17% |
| Professor > Associate Professor | 1 | 17% |
| Professor | 1 | 17% |
| Unknown | 1 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Unspecified | 1 | 17% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 17% |
| Biochemistry, Genetics and Molecular Biology | 1 | 17% |
| Medicine and Dentistry | 1 | 17% |
| Unknown | 2 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 November 2016.
All research outputs
#22,759,802
of 25,374,917 outputs
Outputs from Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences
#4,321
of 5,117 outputs
Outputs of similar age
#355,119
of 415,192 outputs
Outputs of similar age from Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences
#33
of 64 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,117 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 64 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.