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Histones: Annotating Chromatin

Overview of attention for article published in Annual Review of Genetics, December 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

Mentioned by

blogs
1 blog
patent
1 patent
wikipedia
1 Wikipedia page
googleplus
1 Google+ user

Citations

dimensions_citation
703 Dimensions

Readers on

mendeley
989 Mendeley
citeulike
11 CiteULike
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Title
Histones: Annotating Chromatin
Published in
Annual Review of Genetics, December 2009
DOI 10.1146/annurev.genet.032608.103928
Pubmed ID
Authors

Eric I. Campos, Danny Reinberg

Abstract

Chromatin is a highly regulated nucleoprotein complex through which genetic material is structured and maneuvered to elicit cellular processes, including transcription, cell division, differentiation, and DNA repair. In eukaryotes, the core of this structure is composed of nucleosomes, or repetitive histone octamer units typically enfolded by 147 base pairs of DNA. DNA is arranged and indexed through these nucleosomal structures to adjust local chromatin compaction and accessibility. Histones are subject to multiple covalent posttranslational modifications, some of which alter intrinsic chromatin properties, others of which present or hinder binding modules for non-histone, chromatin-modifying complexes. Although certain histone marks correlate with different biological outputs, we have yet to fully appreciate their effects on transcription and other cellular processes. Tremendous advancements over the past years have uncovered intriguing histone-related matters and raised important related questions. This review revisits past breakthroughs and discusses novel developments that pertain to histone posttranslational modifications and the affects they have on transcription and DNA packaging.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 989 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 21 2%
Germany 5 <1%
United Kingdom 5 <1%
Netherlands 4 <1%
Mexico 4 <1%
Spain 4 <1%
Canada 4 <1%
France 3 <1%
India 3 <1%
Other 18 2%
Unknown 918 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 308 31%
Researcher 192 19%
Student > Master 106 11%
Student > Bachelor 90 9%
Professor > Associate Professor 51 5%
Other 139 14%
Unknown 103 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 503 51%
Biochemistry, Genetics and Molecular Biology 227 23%
Medicine and Dentistry 50 5%
Immunology and Microbiology 16 2%
Chemistry 16 2%
Other 62 6%
Unknown 115 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 October 2022.
All research outputs
#2,575,019
of 23,575,882 outputs
Outputs from Annual Review of Genetics
#146
of 762 outputs
Outputs of similar age
#12,688
of 168,602 outputs
Outputs of similar age from Annual Review of Genetics
#7
of 18 outputs
Altmetric has tracked 23,575,882 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 762 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 168,602 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.