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Effectiveness of pandemic influenza A/H1N1 vaccine for prevention of otitis media in children

Overview of attention for article published in European Journal of Pediatrics, September 2012
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Title
Effectiveness of pandemic influenza A/H1N1 vaccine for prevention of otitis media in children
Published in
European Journal of Pediatrics, September 2012
DOI 10.1007/s00431-012-1797-2
Pubmed ID
Authors

Bahar Çuhaci Çakir, Ufuk Beyazova, Yusuf Kemal Kemaloğlu, Seçil Özkan, Bülent Gündüz, Ali Özdek

Abstract

Our aim was to evaluate effectiveness of pandemic influenza A/H1N1 vaccine in preventing acute otitis media (AOM) and/or otitis media with effusion (OME), in a randomized, prospective and single-blind study conducted in the children aged of 6-60 months. This study was done between December 1, 2009 and April 30, 2010 during the pandemia between June 2009 and May 2010. On the healthy children, vaccinated against pandemic influenza A/H1N1 and age-matched unvaccinated controls, the rate of AOM, OME, and any otitis media (OM) attack (sum of AOM and OME attacks) confirmed by otoscopic and tympanometric examination, and their associations with risk factors were looked for. Otoscopic and tympanometric evaluation was done twice within the follow-up period of 4-8 weeks. Totally 46 vaccinated and 46 unvaccinated healthy children were enrolled. No difference in rates of AOM, OME, or OM was found between vaccinated and unvaccinated children. But logistic regression analysis revealed that unvaccinated children had 2.9-folds more risk for OME and OM, but not for AOM. Further, male gender and bottle feeding and/or using pacifier revealed significant relationships with AOM. Conclusion: We conclude that pandemic influenza A/H1N1 vaccine prevented OME rather than AOM attacks in children with 6-60 months of age.

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Geographical breakdown

Country Count As %
United States 1 2%
Unknown 49 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 16%
Researcher 7 14%
Student > Ph. D. Student 7 14%
Student > Master 6 12%
Professor > Associate Professor 2 4%
Other 3 6%
Unknown 17 34%
Readers by discipline Count As %
Medicine and Dentistry 18 36%
Nursing and Health Professions 5 10%
Agricultural and Biological Sciences 3 6%
Biochemistry, Genetics and Molecular Biology 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 4 8%
Unknown 18 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2013.
All research outputs
#20,191,579
of 22,708,120 outputs
Outputs from European Journal of Pediatrics
#3,419
of 3,674 outputs
Outputs of similar age
#153,096
of 172,067 outputs
Outputs of similar age from European Journal of Pediatrics
#29
of 40 outputs
Altmetric has tracked 22,708,120 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
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