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Use of glucose-lowering drugs and risk of fracture in patients with type 2 diabetes

Overview of attention for article published in BONE, November 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

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1 news outlet
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20 X users
facebook
5 Facebook pages

Citations

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44 Dimensions

Readers on

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48 Mendeley
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Title
Use of glucose-lowering drugs and risk of fracture in patients with type 2 diabetes
Published in
BONE, November 2016
DOI 10.1016/j.bone.2016.11.026
Pubmed ID
Authors

Jakob Starup-Linde, Søren Gregersen, Morten Frost, Peter Vestergaard

Abstract

Diabetes mellitus is associated with an increased risk of hip fracture. The aim ofthis cohort study was to investigate whether glucose-lowering drugs influence the risk of hip fracture in patients with incident diabetes. A study was performed on a cohort of patients with incident type 2 diabetes. Diabetes diagnosis was defined using information from the Danish National Patient Registry and reimbursement information of glucose-lowering drugs from the Register of Medicinal Product Statistics. The period of observation was from 01.01.1996 till 31.12.2011. The primary exposure was glucose-lowering drugs and the primary endpoint was hip fracture. Unadjusted, adjusted, and propensity score adjusted Cox regressions were performed. 5244 patients with type 2 diabetes with a mean follow up of 5.5years were included in the study. Use of sulphonylureas within the last 90days was associated with hip fracture in patients with type 2 diabetes, hazard ratio 1.64 (95% confidence interval: 1.54,1.75), whereas ever use of sulohonylyreas was not associated with an increased risk of fractures. Use of sulphonylureas within the last 90days was also associated with an increased risk of fractures at other sites. Use of glitazones within the last 90days was associated with an increased risk of hip fracture, hazard ratio 2.07 (95% confidence interval: 1.39,3.07), whereas ever use was not associated with an increased risk. Current use of sulphonylureas was associated with hip fracture in patients with type 2 diabetes. Speculatively, this may be due to hypoglycemia resulting in falls.

X Demographics

X Demographics

The data shown below were collected from the profiles of 20 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
United States 1 2%
Unknown 46 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 21%
Student > Bachelor 7 15%
Student > Doctoral Student 5 10%
Student > Ph. D. Student 3 6%
Other 2 4%
Other 9 19%
Unknown 12 25%
Readers by discipline Count As %
Medicine and Dentistry 16 33%
Pharmacology, Toxicology and Pharmaceutical Science 4 8%
Nursing and Health Professions 4 8%
Biochemistry, Genetics and Molecular Biology 2 4%
Engineering 2 4%
Other 3 6%
Unknown 17 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 January 2017.
All research outputs
#1,745,330
of 25,732,188 outputs
Outputs from BONE
#119
of 4,355 outputs
Outputs of similar age
#33,464
of 417,412 outputs
Outputs of similar age from BONE
#3
of 49 outputs
Altmetric has tracked 25,732,188 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,355 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 417,412 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.