| Title |
Donor TSH level is associated with clinical pregnancy among oocyte donation cycles
|
|---|---|
| Published in |
Journal of Assisted Reproduction and Genetics, February 2016
|
| DOI | 10.1007/s10815-016-0668-6 |
| Pubmed ID | |
| Authors |
Anatte E. Karmon, Eden R. Cardozo, Irene Souter, Julie Gold, John C. Petrozza, Aaron K. Styer |
| Abstract |
The purpose of the study is to evaluate the association between donor TSH level (independent of recipient TSH level) and recipient pregnancy outcome among fresh donor oocyte IVF cycles. This is a retrospective cohort study investigating 232 consecutive fresh donor-recipient cycles (200 total oocyte donors) at an academic medical center. Main outcome measures include clinical pregnancy and live birth. Cycles were categorized into two groups based on donor TSH level (< 2.5 and ≥ 2.5 mIU/L). After controlling for multiple donor and recipient characteristics, the probability of clinical pregnancy was significantly lower among donors with TSH levels ≥2.5 mIU/L compared to those with TSH values <2.5 mIU/L (43.1 %, 95 % CI 28.5-58.9, versus 66.7 %, 95 % CI 58.6-73.9, respectively, p = 0.01). The difference in live birth rates between the two groups did not achieve statistical significance (43.1 %, 95 % CI 28.8-58.6, versus 58.0 %, 95 % CI 50.0-65.6, respectively, p = 0.09). Donor TSH level, independent of recipient TSH level, is associated with recipient clinical pregnancy. These findings suggest that thyroid function may impact the likelihood of pregnancy at the level of the oocyte. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 21 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 4 | 19% |
| Student > Bachelor | 4 | 19% |
| Student > Doctoral Student | 3 | 14% |
| Other | 2 | 10% |
| Professor > Associate Professor | 2 | 10% |
| Other | 4 | 19% |
| Unknown | 2 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 11 | 52% |
| Agricultural and Biological Sciences | 3 | 14% |
| Nursing and Health Professions | 2 | 10% |
| Computer Science | 1 | 5% |
| Social Sciences | 1 | 5% |
| Other | 1 | 5% |
| Unknown | 2 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 October 2016.
All research outputs
#19,611,252
of 24,119,703 outputs
Outputs from Journal of Assisted Reproduction and Genetics
#1,199
of 1,697 outputs
Outputs of similar age
#296,903
of 405,232 outputs
Outputs of similar age from Journal of Assisted Reproduction and Genetics
#22
of 29 outputs
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