Title |
The Prevalence of Aortic Calcification on Vertebral Fracture Assessment Imaging Among Patients With Rheumatoid Arthritis
|
---|---|
Published in |
Journal of Clinical Densitometry, March 2013
|
DOI | 10.1016/j.jocd.2013.02.014 |
Pubmed ID | |
Authors |
Ausaf Mohammad, Derek Lohan, Diane Bergin, Sarah Mooney, John Newell, Martin O’Donnell, Robert J. Coughlan, John J. Carey |
Abstract |
Patients with rheumatoid arthritis (RA) are at increased risk of osteoporosis (OP) and cardiovascular disease (CVD). Dual-energy X-ray absorptiometry scans have been validated for identifying patients with RA at risk for fracture. Reliable CVD risk stratification remains an unmet need in this population. Vertebral fracture assessment (VFA)-detected abdominal aortic calcification (AAC) has been validated as a marker of CVD in other populations, but the prevalence among patients with RA is unknown. In this study, we determined the prevalence and severity of AAC on VFA scans in a cohort of patients with RA. AAC was detected in 211 of the 603 (35%) eligible subjects; 24% were graded as severe. In multivariable analyses, the presence of AAC was significantly associated with longer disease duration and higher disease activity (p<0.05). Further studies are needed on the relationship between AAC and CVD in patients with RA. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 6 | 21% |
Student > Ph. D. Student | 6 | 21% |
Other | 3 | 11% |
Student > Doctoral Student | 3 | 11% |
Researcher | 2 | 7% |
Other | 3 | 11% |
Unknown | 5 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 36% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Business, Management and Accounting | 1 | 4% |
Nursing and Health Professions | 1 | 4% |
Arts and Humanities | 1 | 4% |
Other | 4 | 14% |
Unknown | 10 | 36% |