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The pathobiology of two Indonesian H5N1 avian influenza viruses representing different clade 2.1 sublineages in chickens and ducks

Overview of attention for article published in Comparative Immunology, Microbiology & Infectious Diseases, January 2013
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  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

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3 X users

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37 Mendeley
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Title
The pathobiology of two Indonesian H5N1 avian influenza viruses representing different clade 2.1 sublineages in chickens and ducks
Published in
Comparative Immunology, Microbiology & Infectious Diseases, January 2013
DOI 10.1016/j.cimid.2012.12.001
Pubmed ID
Authors

Hendra Wibawa, John Bingham, Harimurti Nuradji, Sue Lowther, Jean Payne, Jennifer Harper, Frank Wong, Ross Lunt, Akhmad Junaidi, Deborah Middleton, Joanne Meers

Abstract

To determine the pathobiology of Indonesian H5N1 highly pathogenic avian influenza, two viruses representing clades 2.1.1 and 2.1.3 were inoculated into broiler chickens and Pekin ducks via the eyes, nostrils and oropharynx. In chickens, both viruses produced fulminant disease; tissue tropism was broad but predominantly endothelial and viral loads in tissues were high. Except for one case of meningoencephalitis, the infection in ducks was sub-clinical, leading only to seroconversion. In these ducks, virus and viral antigen occurred in lower amounts, mainly in the respiratory tract (airsac and sinuses), prior to day 7 after inoculation. During clinical disease, chickens shed high virus titres orally and cloacally. Ducks intermittently shed low virus titres from the oral route for up to 8 days post-inoculation. We discuss the significance of the data for understanding the pathogenesis and pathobiology of Indonesian H5N1 in chickens and ducks.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 5%
Indonesia 1 3%
Bangladesh 1 3%
Unknown 33 89%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 19%
Researcher 5 14%
Student > Bachelor 4 11%
Student > Master 4 11%
Librarian 3 8%
Other 9 24%
Unknown 5 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 32%
Veterinary Science and Veterinary Medicine 7 19%
Medicine and Dentistry 3 8%
Immunology and Microbiology 2 5%
Nursing and Health Professions 1 3%
Other 8 22%
Unknown 4 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 May 2013.
All research outputs
#15,517,312
of 25,373,627 outputs
Outputs from Comparative Immunology, Microbiology & Infectious Diseases
#301
of 830 outputs
Outputs of similar age
#175,067
of 289,012 outputs
Outputs of similar age from Comparative Immunology, Microbiology & Infectious Diseases
#4
of 14 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 830 research outputs from this source. They receive a mean Attention Score of 2.5. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,012 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.