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PIK3CA and PTEN Gene and Exon Mutation-Specific Clinicopathologic and Molecular Associations in Colorectal Cancer

Overview of attention for article published in Clinical Cancer Research, June 2013
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Title
PIK3CA and PTEN Gene and Exon Mutation-Specific Clinicopathologic and Molecular Associations in Colorectal Cancer
Published in
Clinical Cancer Research, June 2013
DOI 10.1158/1078-0432.ccr-12-3614
Pubmed ID
Authors

Fiona L. Day, Robert N. Jorissen, Lara Lipton, Dmitri Mouradov, Anuratha Sakthianandeswaren, Michael Christie, Shan Li, Cary Tsui, Jeannie Tie, Jayesh Desai, Zheng-Zhou Xu, Peter Molloy, Vicki Whitehall, Barbara A. Leggett, Ian T. Jones, Stephen McLaughlin, Robyn L. Ward, Nicholas J. Hawkins, Andrew R. Ruszkiewicz, James Moore, Dana Busam, Qi Zhao, Robert L. Strausberg, Peter Gibbs, Oliver M. Sieber

Abstract

PIK3CA and PTEN mutations are prevalent in colorectal cancer and potential markers of response to mitogen-activated protein/extracellular signal-regulated kinase inhibitors and anti-EGF receptor antibody therapy. Relationships between phosphoinositide 3-kinase (PI3K) pathway mutation, clinicopathologic characteristics, molecular features, and prognosis remain controversial.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Unknown 118 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 31 26%
Student > Master 18 15%
Student > Ph. D. Student 15 13%
Student > Bachelor 11 9%
Other 10 8%
Other 14 12%
Unknown 20 17%
Readers by discipline Count As %
Medicine and Dentistry 49 41%
Biochemistry, Genetics and Molecular Biology 24 20%
Agricultural and Biological Sciences 16 13%
Arts and Humanities 2 2%
Engineering 2 2%
Other 6 5%
Unknown 20 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 June 2013.
All research outputs
#17,724,588
of 22,760,687 outputs
Outputs from Clinical Cancer Research
#10,956
of 12,571 outputs
Outputs of similar age
#141,391
of 196,946 outputs
Outputs of similar age from Clinical Cancer Research
#134
of 183 outputs
Altmetric has tracked 22,760,687 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,571 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,946 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 183 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.