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Mendeley readers
Attention Score in Context
| Title |
A combined method for producing homogeneous glycoproteins with eukaryotic N-glycosylation
|
|---|---|
| Published in |
Nature Chemical Biology, February 2010
|
| DOI | 10.1038/nchembio.314 |
| Pubmed ID | |
| Authors |
Flavio Schwarz, Wei Huang, Cishan Li, Benjamin L Schulz, Christian Lizak, Alessandro Palumbo, Shin Numao, Dario Neri, Markus Aebi, Lai-Xi Wang |
| Abstract |
We describe a new method for producing homogeneous eukaryotic N-glycoproteins. The method involves the engineering and functional transfer of the Campylobacter jejuni glycosylation machinery in Escherichia coli to express glycosylated proteins with the key GlcNAc-Asn linkage. The bacterial glycans were then trimmed and remodeled in vitro by enzymatic transglycosylation to fulfill a eukaryotic N-glycosylation. It provides a potentially general platform for producing eukaryotic N-glycoproteins. |
Mendeley readers
The data shown below were compiled from readership statistics for 195 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 2% |
| Switzerland | 2 | 1% |
| France | 1 | <1% |
| Germany | 1 | <1% |
| Italy | 1 | <1% |
| Austria | 1 | <1% |
| United Kingdom | 1 | <1% |
| Ireland | 1 | <1% |
| China | 1 | <1% |
| Other | 3 | 2% |
| Unknown | 179 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 58 | 30% |
| Student > Ph. D. Student | 52 | 27% |
| Student > Master | 21 | 11% |
| Student > Bachelor | 11 | 6% |
| Student > Postgraduate | 9 | 5% |
| Other | 27 | 14% |
| Unknown | 17 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 93 | 48% |
| Chemistry | 32 | 16% |
| Biochemistry, Genetics and Molecular Biology | 27 | 14% |
| Chemical Engineering | 8 | 4% |
| Engineering | 6 | 3% |
| Other | 11 | 6% |
| Unknown | 18 | 9% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2024.
All research outputs
#3,774,310
of 23,477,147 outputs
Outputs from Nature Chemical Biology
#1,709
of 3,134 outputs
Outputs of similar age
#16,146
of 95,084 outputs
Outputs of similar age from Nature Chemical Biology
#18
of 36 outputs
Altmetric has tracked 23,477,147 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,134 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.1. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,084 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.