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Mendeley readers
Attention Score in Context
| Title |
Crotalaria medicaginea Associated with Horse Deaths in Northern Australia: New Pyrrolizidine Alkaloids
|
|---|---|
| Published in |
Journal of Agricultural & Food Chemistry, October 2011
|
| DOI | 10.1021/jf203147x |
| Pubmed ID | |
| Authors |
Mary T. Fletcher, Patricia Y. Hayes, Michael J. Somerville, James J. De Voss |
| Abstract |
Crotalaria medicaginea has been implicated in horse poisoning in grazing regions of central-west Queensland, which resulted in the deaths of more than 35 horses from hepatotoxicosis in 2010. Liver pathology was suggestive of pyrrolizidine alkaloidosis, and we report here the isolation of two previously uncharacterized pyrrolizidine alkaloids from C. medicaginea plant specimens collected from pastures where the horses died. The first alkaloid was shown by mass spectometric and NMR analyses to be 1β,2β-epoxy-7β-hydroxy-1α-methoxymethyl-8α-pyrrolizidine, which, like other alkaloids previously isolated from C. medicaginea, lacks the requisite functionality for hepatotoxcity. The second alkaloid isolated in this investigation was a new macrocyclic diester of otonecine, which we have named cromedine. The (1)H and (13)C NMR spectra of cromedine were fully assigned by 2D NMR techniques and allowed the constitution of the macrocyclic diester to be assigned unambiguously. C. medicaginea specimens implicated in this investigation do not belong to any of the three recognized Australian varieties (C. medicaginea var. neglecta, C. medicaginea var. medicaginea, and C. medicaginea var. linearis) and appear to be a local variant or form, referred to here as C. medicaginea (chemotype cromedine). |
Mendeley readers
The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 17 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 3 | 18% |
| Student > Ph. D. Student | 3 | 18% |
| Professor > Associate Professor | 2 | 12% |
| Researcher | 2 | 12% |
| Student > Bachelor | 1 | 6% |
| Other | 0 | 0% |
| Unknown | 6 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 5 | 29% |
| Agricultural and Biological Sciences | 3 | 18% |
| Biochemistry, Genetics and Molecular Biology | 1 | 6% |
| Medicine and Dentistry | 1 | 6% |
| Veterinary Science and Veterinary Medicine | 1 | 6% |
| Other | 0 | 0% |
| Unknown | 6 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2011.
All research outputs
#5,302,769
of 25,728,855 outputs
Outputs from Journal of Agricultural & Food Chemistry
#3,424
of 19,236 outputs
Outputs of similar age
#28,705
of 146,793 outputs
Outputs of similar age from Journal of Agricultural & Food Chemistry
#38
of 145 outputs
Altmetric has tracked 25,728,855 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 19,236 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 146,793 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 145 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.