Title |
Synthesis-View: visualization and interpretation of SNP association results for multi-cohort, multi-phenotype data and meta-analysis
|
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Published in |
BioData Mining, December 2010
|
DOI | 10.1186/1756-0381-3-10 |
Pubmed ID | |
Authors |
Sarah A Pendergrass, Scott M Dudek, Dana C Crawford, Marylyn D Ritchie |
Abstract |
Initial genome-wide association study (GWAS) discoveries are being further explored through the use of large cohorts across multiple and diverse populations involving meta-analyses within large consortia and networks. Many of the additional studies characterize less than 100 single nucleotide polymorphisms (SNPs), often include multiple and correlated phenotypic measurements, and can include data from multiple-sites, multiple-studies, as well as multiple race/ethnicities. New approaches for visualizing resultant data are necessary in order to fully interpret results and obtain a broad view of the trends between DNA variation and phenotypes, as well as provide information on specific SNP and phenotype relationships. |
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Geographical breakdown
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Netherlands | 2 | 4% |
United Kingdom | 1 | 2% |
United States | 1 | 2% |
Australia | 1 | 2% |
Unknown | 45 | 90% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 11 | 22% |
Researcher | 9 | 18% |
Professor | 4 | 8% |
Student > Doctoral Student | 3 | 6% |
Student > Postgraduate | 3 | 6% |
Other | 11 | 22% |
Unknown | 9 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 14 | 28% |
Medicine and Dentistry | 9 | 18% |
Computer Science | 8 | 16% |
Biochemistry, Genetics and Molecular Biology | 5 | 10% |
Linguistics | 1 | 2% |
Other | 5 | 10% |
Unknown | 8 | 16% |