| Title |
Neural correlates of rumination in adolescents with remitted major depressive disorder and healthy controls
|
|---|---|
| Published in |
Cognitive, Affective, & Behavioral Neuroscience, December 2016
|
| DOI | 10.3758/s13415-016-0486-4 |
| Pubmed ID | |
| Authors |
Katie L. Burkhouse, Rachel H. Jacobs, Amy T. Peters, Olu Ajilore, Edward R. Watkins, Scott A. Langenecker |
| Abstract |
The aim of the present study was to use fMRI to examine the neural correlates of engaging in rumination among a sample of remitted depressed adolescents, a population at high risk for future depressive relapse. A rumination induction task was used to assess differences in the patterns of neural activation during rumination versus a distraction condition among 26 adolescents in remission from major depressive disorder (rMDD) and in 15 healthy control adolescents. Self-report depression and rumination, as well as clinician-rated depression, were also assessed among all participants. All of the participants recruited regions in the default mode network (DMN), including the posterior cingulate cortex, medial prefrontal cortex, inferior parietal lobe, and medial temporal gyrus, during rumination. Increased activation in these regions during rumination was correlated with increased self-report rumination and symptoms of depression across all participants. Adolescents with rMDD also exhibited greater activation in regions involved in visual, somatosensory, and emotion processing than did healthy peers. The present findings suggest that during ruminative thought, adolescents with rMDD are characterized by increased recruitment of regions within the DMN and in areas involved in visual, somatosensory, and emotion processing. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 157 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 157 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 30 | 19% |
| Student > Ph. D. Student | 26 | 17% |
| Researcher | 22 | 14% |
| Student > Bachelor | 12 | 8% |
| Student > Postgraduate | 5 | 3% |
| Other | 16 | 10% |
| Unknown | 46 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 46 | 29% |
| Medicine and Dentistry | 17 | 11% |
| Neuroscience | 15 | 10% |
| Social Sciences | 4 | 3% |
| Nursing and Health Professions | 3 | 2% |
| Other | 15 | 10% |
| Unknown | 57 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2017.
All research outputs
#2,005,854
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Outputs from Cognitive, Affective, & Behavioral Neuroscience
#95
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Outputs of similar age
#38,647
of 416,422 outputs
Outputs of similar age from Cognitive, Affective, & Behavioral Neuroscience
#2
of 19 outputs
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