| Title |
An easy-to-use wound dressing gelatin-bioactive nanoparticle gel and its preliminary in vivo study
|
|---|---|
| Published in |
Journal of Materials Science: Materials in Medicine, December 2016
|
| DOI | 10.1007/s10856-016-5823-1 |
| Pubmed ID | |
| Authors |
Chen Wang, Feiyan Zhu, Yang Cui, Huihui Ren, Yue Xie, Ailing Li, Lijun Ji, Xiaozhong Qu, Dong Qiu, Zhenzhong Yang |
| Abstract |
Beyond promoting hard tissue repairing, bioactive glasses (BGs) have also been proved to be beneficial for wound healing. Nano-scale BGs prepared by sol-gel method were found to have a better performance as they have a larger specific surface area. In this work, bioactive nanoparticles (nBPs) with mean diameter of 12 nm (BP-12) instead of conventional BGs were mixed with gelatin to form an easy-to-use hydrogel as a dressing for skin wound. It was found that the composite of BP-12 and gelatin could form a hydrogel (BP-12/Gel) under 25 °C, which showed pronounced thixotropy at a practically accessible shear rate, therefore become easy to be used for wound cover. In vitro, the composite hydrogel of BP-12 and gelatin had good biocompatibility with the fibroblast cells. In vivo, rapid cutaneous-tissue regeneration and tissue-structure formation within 7 days was observed in the wound-healing experiment performed in rats. This hydrogel is thus a promising easy-to-use wound dressing material. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 55 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 16 | 29% |
| Student > Ph. D. Student | 8 | 15% |
| Student > Bachelor | 5 | 9% |
| Researcher | 4 | 7% |
| Other | 4 | 7% |
| Other | 8 | 15% |
| Unknown | 10 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Materials Science | 10 | 18% |
| Engineering | 9 | 16% |
| Agricultural and Biological Sciences | 6 | 11% |
| Medicine and Dentistry | 5 | 9% |
| Biochemistry, Genetics and Molecular Biology | 4 | 7% |
| Other | 9 | 16% |
| Unknown | 12 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 December 2016.
All research outputs
#15,398,970
of 22,908,162 outputs
Outputs from Journal of Materials Science: Materials in Medicine
#1,045
of 1,404 outputs
Outputs of similar age
#250,764
of 416,052 outputs
Outputs of similar age from Journal of Materials Science: Materials in Medicine
#9
of 11 outputs
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So far Altmetric has tracked 1,404 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
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