Title |
The role of cytokines in the development of atherosclerosis
|
---|---|
Published in |
Biochemistry, November 2016
|
DOI | 10.1134/s0006297916110134 |
Pubmed ID | |
Authors |
A. R. Fatkhullina, I. O. Peshkova, E. K. Koltsova |
Abstract |
Atherosclerosis contributes to the development of many cardiovascular diseases, which remain the leading cause of death in developed countries. Atherosclerosis is a chronic inflammatory disease of large and medium-sized arteries. It is caused by dyslipidemia and mediated by both innate and adaptive immune responses. Inflammation is a key factor at all stages of atherosclerosis progression. Cells involved in pathogenesis of atherosclerosis were shown to be activated by soluble factors, cytokines, that strongly influence the disease development. Pro-inflammatory cytokines accelerate atherosclerosis progression, while anti-inflammatory cytokines ameliorate the disease. In this review, we discuss the latest findings on the role of cytokines in the development and progression of atherosclerosis. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 287 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 60 | 21% |
Student > Ph. D. Student | 39 | 14% |
Student > Master | 25 | 9% |
Student > Doctoral Student | 20 | 7% |
Researcher | 16 | 6% |
Other | 37 | 13% |
Unknown | 90 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 60 | 21% |
Medicine and Dentistry | 35 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 23 | 8% |
Agricultural and Biological Sciences | 17 | 6% |
Immunology and Microbiology | 16 | 6% |
Other | 36 | 13% |
Unknown | 100 | 35% |