| Title |
Anti-NMDA-Receptor Encephalitis: Case Report and Literature Review of an Under-Recognized Condition
|
|---|---|
| Published in |
Journal of General Internal Medicine, February 2011
|
| DOI | 10.1007/s11606-011-1641-9 |
| Pubmed ID | |
| Authors |
Gregory S. Day, Sasha M. High, Bianca Cot, David F. Tang-Wai |
| Abstract |
Anti-N-methyl-D-aspartate receptor (anti-NMDA-R) encephalitis is an immune-mediated syndrome that remains under-recognized despite a growing body of literature. This syndrome has been predominantly described in young females with a constellation of symptoms, including personality changes, autonomic dysfunction and neurologic decompensation. It is commonly associated with mature ovarian teratomas. We describe the classic presentation of anti-NMDA-R encephalitis in three dramatically different patients: Case A, a young woman with ovarian teratoma; Case B, the eldest case reported to date; and Case C, a young male with no identifiable tumor. We review the literature summarizing the differential diagnosis, investigative approach, treatment options and challenges inherent to this disorder. We advocate good supportive care, involvement of multiple health disciplines and use of immune-modulating therapies in patient management. These cases underscore the need for increased awareness and high diagnostic suspicion when approaching the patient with suspected viral encephalitis. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 2 | 2% |
| Colombia | 1 | <1% |
| Canada | 1 | <1% |
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 113 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 16 | 13% |
| Student > Bachelor | 14 | 12% |
| Researcher | 13 | 11% |
| Student > Ph. D. Student | 12 | 10% |
| Student > Postgraduate | 11 | 9% |
| Other | 33 | 28% |
| Unknown | 20 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 64 | 54% |
| Agricultural and Biological Sciences | 8 | 7% |
| Neuroscience | 6 | 5% |
| Psychology | 6 | 5% |
| Nursing and Health Professions | 4 | 3% |
| Other | 6 | 5% |
| Unknown | 25 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 June 2014.
All research outputs
#14,759,948
of 23,911,072 outputs
Outputs from Journal of General Internal Medicine
#5,426
of 7,806 outputs
Outputs of similar age
#144,808
of 190,658 outputs
Outputs of similar age from Journal of General Internal Medicine
#33
of 45 outputs
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