| Title |
Structure and evolutionary origins of the CMG complex
|
|---|---|
| Published in |
Chromosoma, February 2013
|
| DOI | 10.1007/s00412-013-0397-x |
| Pubmed ID | |
| Authors |
Silvia Onesti, Stuart A. MacNeill |
| Abstract |
The CMG (Cdc45-MCM-GINS) complex is the eukaryotic replicative helicase, the enzyme that unwinds double-stranded DNA at replication forks. All three components of the CMG complex are essential for its function, but only in the case of MCM, the molecular motor that harnesses the energy of ATP hydrolysis to catalyse strand separation, is that function clear. Here, we review current knowledge of the three-dimensional structure of the CMG complex and its components and highlight recent advances in our understanding of its evolutionary origins. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 2% |
| Unknown | 63 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 15 | 23% |
| Student > Ph. D. Student | 10 | 16% |
| Student > Master | 10 | 16% |
| Researcher | 8 | 13% |
| Student > Doctoral Student | 6 | 9% |
| Other | 7 | 11% |
| Unknown | 8 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 28 | 44% |
| Agricultural and Biological Sciences | 24 | 38% |
| Chemistry | 2 | 3% |
| Medicine and Dentistry | 2 | 3% |
| Unknown | 8 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 May 2013.
All research outputs
#18,338,946
of 22,710,079 outputs
Outputs from Chromosoma
#658
of 756 outputs
Outputs of similar age
#238,071
of 307,711 outputs
Outputs of similar age from Chromosoma
#4
of 4 outputs
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