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Menstrual Cycle Characteristics and History of Ovulatory Infertility in Relation to Breast Cancer Risk in a Large Cohort of US Women

Overview of attention for article published in American Journal of Epidemiology, April 1998
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Title
Menstrual Cycle Characteristics and History of Ovulatory Infertility in Relation to Breast Cancer Risk in a Large Cohort of US Women
Published in
American Journal of Epidemiology, April 1998
DOI 10.1093/oxfordjournals.aje.a009504
Pubmed ID
Authors

Miriam Garland, David J. Hunter, Graham A. Colditz, JoAnn E. Manson, Meir J. Stampfer, Donna Spiegelman, Frank Speizer, Walter C. Willett

Abstract

Menstrual cycle characteristics and ovulatory infertility were evaluated in relation to breast cancer risk among 116,678 women in the Nurses' Health Study II, a prospective cohort study of female registered nurses who were aged 25-42 years and living in 14 US states at enrollment in 1989. During 396,299 person-years of follow-up between return of the baseline questionnaire and June 1993, 251 cases of breast cancer were identified in this cohort. The multivariate relative risk (RR) associated with age at menarche > 13 years compared with age < or = 12 years was 0.66 (95% confidence interval (CI) 0.44-0.99). Short and long menstrual cycle lengths at ages 18-22 years were associated with reduced risk. Compared with menstrual cycle length 26-31 days, the multivariate relative risks (95% CIs) for more extreme cycle lengths were: < 26 days, 0.50 (0.25-0.98); 32-39 days, 0.81 (0.51-1.28); and > 39 days or too irregular for estimation of a usual cycle length, 0.41 (0.18-0.94). The multivariate relative risk associated with a history of ovulatory infertility, compared with no such history, was 0.41 (95% CI 0.18-0.93). These results are consistent with the hypothesis that reduced exposure to ovulatory menstrual cycles provides a protective effect against breast cancer.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Portugal 1 3%
Unknown 28 93%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 4 13%
Student > Doctoral Student 3 10%
Researcher 3 10%
Student > Bachelor 2 7%
Unspecified 2 7%
Other 6 20%
Unknown 10 33%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 20%
Medicine and Dentistry 4 13%
Unspecified 2 7%
Biochemistry, Genetics and Molecular Biology 1 3%
Psychology 1 3%
Other 3 10%
Unknown 13 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 January 2012.
All research outputs
#7,495,032
of 22,914,829 outputs
Outputs from American Journal of Epidemiology
#4,828
of 9,060 outputs
Outputs of similar age
#10,038
of 33,117 outputs
Outputs of similar age from American Journal of Epidemiology
#29
of 51 outputs
Altmetric has tracked 22,914,829 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,060 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.0. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
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We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.