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Increased levels of the oxidative stress biomarker 8-iso-prostaglandin F2α in wastewater associated with tobacco use

Overview of attention for article published in Scientific Reports, December 2016
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

news
1 news outlet
blogs
1 blog
twitter
4 X users
googleplus
1 Google+ user

Citations

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64 Dimensions

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78 Mendeley
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Title
Increased levels of the oxidative stress biomarker 8-iso-prostaglandin F2α in wastewater associated with tobacco use
Published in
Scientific Reports, December 2016
DOI 10.1038/srep39055
Pubmed ID
Authors

Yeonsuk Ryu, Emma Gracia-Lor, Richard Bade, J. A. Baz-Lomba, Jørgen G. Bramness, Sara Castiglioni, Erika Castrignanò, Ana Causanilles, Adrian Covaci, Pim de Voogt, Felix Hernandez, Barbara Kasprzyk-Hordern, Juliet Kinyua, Ann-Kathrin McCall, Christoph Ort, Benedek G. Plósz, Pedram Ramin, Nikolaos I. Rousis, Malcolm J. Reid, Kevin V. Thomas

Abstract

Wastewater analysis has been demonstrated to be a complementary approach for assessing the overall patterns of drug use by a population while the full potential of wastewater-based epidemiology has yet to be explored. F2-isoprostanes are a prototype wastewater biomarker to study the cumulative oxidative stress at a community level. In this work, 8-iso-prostaglandin F2α (8-iso-PGF2α) was analysed in raw 24 h-composite wastewater samples collected from 4 Norwegian and 7 other European cities in 2014 and 2015. Using the same samples, biomarkers of alcohol (ethyl sulfate) and tobacco (trans-3'-hydroxycotinine) use were also analysed to investigate any possible correlation between 8-iso-PGF2α and the consumption of the two drugs. The estimated per capita daily loads of 8-iso-PGF2α in the 11 cities ranged between 2.5 and 9.9 mg/day/1000 inhabitants with a population-weighted mean of 4.8 mg/day/1000 inhabitants. There were no temporal trends observed in the levels of 8-iso-PGF2α, however, spatial differences were found at the inter-city level correlating to the degree of urbanisation. The 8-iso-PGF2α mass load was found to be strongly associated with that of trans-3'-hydroxycotinine while it showed no correlation with ethyl sulfate. The present study shows the potential for 8-iso-PGF2α as a wastewater biomarker for the assessment of community public health.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
Switzerland 1 1%
Unknown 76 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 22%
Researcher 10 13%
Student > Master 10 13%
Other 6 8%
Student > Doctoral Student 3 4%
Other 11 14%
Unknown 21 27%
Readers by discipline Count As %
Environmental Science 11 14%
Chemistry 8 10%
Engineering 6 8%
Medicine and Dentistry 5 6%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Other 11 14%
Unknown 34 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 March 2021.
All research outputs
#1,643,770
of 22,914,829 outputs
Outputs from Scientific Reports
#15,349
of 123,793 outputs
Outputs of similar age
#35,885
of 420,880 outputs
Outputs of similar age from Scientific Reports
#475
of 3,516 outputs
Altmetric has tracked 22,914,829 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 123,793 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 420,880 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 3,516 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.