Title |
How Does Antiretroviral Treatment Attenuate the Stigma of HIV? Evidence from a Cohort Study in Rural Uganda
|
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Published in |
AIDS and Behavior, May 2013
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DOI | 10.1007/s10461-013-0503-3 |
Pubmed ID | |
Authors |
Alexander C. Tsai, David R. Bangsberg, Mwebesa Bwana, Jessica E. Haberer, Edward A. Frongillo, Conrad Muzoora, Elias Kumbakumba, Peter W. Hunt, Jeffrey N. Martin, Sheri D. Weiser |
Abstract |
Program implementers and qualitative researchers have described how increasing availability of HIV antiretroviral therapy (ART) is associated with improvements in psychosocial health and internalized stigma. To determine whether, and through what channels, ART reduces internalized stigma, we analyzed data from 262 HIV-infected, treatment-naïve persons in rural Uganda followed from ART initiation over a median of 3.4 years. We fitted Poisson regression models with cluster-correlated robust estimates of variance, specifying internalized stigma as the dependent variable, adjusting for time on treatment as well as socio-demographic, clinical, and psychosocial variables. Over time on treatment, internalized stigma declined steadily, with the largest decline observed during the first 2 years of treatment. This trend remained statistically significant after multivariable adjustment (χ(2) = 28.3; P = 0.03), and appeared to be driven by ART-induced improvements in HIV symptom burden, physical and psychological wellbeing, and depression symptom severity. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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South Africa | 1 | <1% |
Unknown | 149 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 30 | 20% |
Researcher | 28 | 19% |
Student > Ph. D. Student | 14 | 9% |
Student > Bachelor | 12 | 8% |
Student > Postgraduate | 8 | 5% |
Other | 20 | 13% |
Unknown | 38 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 31 | 21% |
Social Sciences | 21 | 14% |
Nursing and Health Professions | 19 | 13% |
Psychology | 19 | 13% |
Agricultural and Biological Sciences | 3 | 2% |
Other | 12 | 8% |
Unknown | 45 | 30% |