Title |
Hypomagnesemia as a possible explanation behind episodes of severe pain in cancer patients receiving palliative care
|
---|---|
Published in |
Supportive Care in Cancer, December 2012
|
DOI | 10.1007/s00520-012-1669-3 |
Pubmed ID | |
Authors |
José Mario López-Saca, José Maria López-Picazo, Ana Larumbe, Juli Urdíroz, Carlos Centeno |
Abstract |
Within an oncology setting, certain chemotherapy drugs, such as cisplatin, may lead to magnesium loss causing nephropathy. Neurological and cardiovascular symptoms caused by hypomagnesaemia are well known. The relationship between serious hypomagnesemia and severe pain is not well documented but nevertheless, when faced with unexplained episodes of pain which do not respond to powerful analgesics, it is important to review blood magnesium levels. We present two cases of opioid-refractory pain attacks. Patients received drugs which have been linked to hypomagnesemia. In both cases, endovenous magnesium replacement led to a drastic improvement in pain management. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 41 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 8 | 20% |
Student > Ph. D. Student | 6 | 15% |
Student > Bachelor | 5 | 12% |
Researcher | 5 | 12% |
Student > Postgraduate | 5 | 12% |
Other | 7 | 17% |
Unknown | 5 | 12% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 34% |
Nursing and Health Professions | 9 | 22% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
Agricultural and Biological Sciences | 2 | 5% |
Psychology | 2 | 5% |
Other | 7 | 17% |
Unknown | 5 | 12% |