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Prognostic Importance of Low Admission Serum Creatinine Concentration for Mortality in Hospitalized Patients

Overview of attention for article published in American Journal of Medicine, December 2016
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

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31 X users

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57 Mendeley
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Title
Prognostic Importance of Low Admission Serum Creatinine Concentration for Mortality in Hospitalized Patients
Published in
American Journal of Medicine, December 2016
DOI 10.1016/j.amjmed.2016.11.020
Pubmed ID
Authors

Charat Thongprayoon, Wisit Cheungpasitporn, Wonngarm Kittanamongkolchai, Andrew M. Harrison, Kianoush Kashani

Abstract

To assess the association between low serum creatinine value at admission and in-hospital mortality in hospitalized patients. This was a retrospective single-center cohort study conducted at a tertiary referral hospital. All hospitalized adult patients in 2011 through 2013 who had an admission creatinine value available were identified for inclusion in this study. Admission creatinine value was categorized into 7 groups: ≤0.4, 0.5-0.6, 0.7-0.8, 0.9-1.0, 1.1-1.2, 1.3-1.4, and ≥1.5 mg/dL. The primary outcome was in-hospital mortality. Logistic regression analysis was performed to obtain the odds ratio of in-hospital mortality for the various admission creatinine levels, using creatinine value of 0.7-0.8 mg/dL as the reference group in analysis of all patient and females and of 0.9-1.0 mg/dL in analysis of males because it was associated with lowest in-hospital mortality. Of 73,994 included patients, 973 (1.3%) died in the hospital. The association between different categories of admission creatinine value and in-hospital mortality assumed a U-shaped distribution, with both low and high creatinine values associated with higher in-hospital mortality. After adjustment for age, sex, ethnicity, principal diagnosis, and comorbid conditions, very low creatinine value (≤0.4 mg/dL) was significantly associated with increased mortality (odds ratio, 3.29; 95% CI, 2.08-5.00), exceeding the risk related to markedly increased creatinine value of ≥1.5 mg/dL (odds ratio, 2.56; 95% CI, 2.07-3.17). The association remained significant in subgroup analysis of male and female patients. Low creatinine value at admission is independently associated with increased in-hospital mortality in hospitalized patients.

X Demographics

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The data shown below were collected from the profiles of 31 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 56 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 11%
Student > Doctoral Student 4 7%
Student > Bachelor 4 7%
Researcher 4 7%
Student > Ph. D. Student 4 7%
Other 9 16%
Unknown 26 46%
Readers by discipline Count As %
Medicine and Dentistry 16 28%
Nursing and Health Professions 3 5%
Engineering 3 5%
Agricultural and Biological Sciences 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 2 4%
Unknown 31 54%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 August 2017.
All research outputs
#1,573,984
of 25,374,917 outputs
Outputs from American Journal of Medicine
#729
of 7,887 outputs
Outputs of similar age
#31,386
of 422,543 outputs
Outputs of similar age from American Journal of Medicine
#12
of 108 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,887 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.2. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 422,543 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 108 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.