| Title |
A Review of Clinical Practice Guidelines for the Management of Hypertriglyceridemia: A Focus on High Dose Omega-3 Fatty Acids
|
|---|---|
| Published in |
Advances in Therapy, December 2016
|
| DOI | 10.1007/s12325-016-0462-y |
| Pubmed ID | |
| Authors |
Dean G. Karalis |
| Abstract |
Cardiovascular (CV) disease remains the leading cause of preventable death in the US. Hyperlipidemia is a major modifiable risk factor for CV disease, and after numerous clinical trials have demonstrated that reductions in low-density lipoprotein (LDL) cholesterol with statin therapy can prevent major adverse CV events, statins have emerged as the drug of choice to lower LDL cholesterol and reduce CV risk. However, some statin-treated patients remain at high residual risk of CV events despite achieving low LDL cholesterol levels, especially if their triglyceride (TG) levels are elevated or their high-density lipoprotein (HDL) cholesterol levels low. Evidence from genetic and observational studies has linked elevated TG levels to an increased risk of CV events. Furthermore, very high TG levels are associated with acute pancreatitis. Consequently, several clinical practice guidelines provide recommendations for the management and treatment of high and very high TG levels. This review focuses on the clinical practice guidelines for the management of hypertriglyceridemia and the role of prescription omega-3 fatty acids in preventing pancreatitis and CV disease in individuals with high and very high TG levels. |
X Demographics
The data shown below were collected from the profiles of 20 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Venezuela, Bolivarian Republic of | 3 | 15% |
| United States | 3 | 15% |
| Brazil | 2 | 10% |
| Netherlands | 2 | 10% |
| France | 1 | 5% |
| Pakistan | 1 | 5% |
| Spain | 1 | 5% |
| Mexico | 1 | 5% |
| Unknown | 6 | 30% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 13 | 65% |
| Science communicators (journalists, bloggers, editors) | 3 | 15% |
| Scientists | 3 | 15% |
| Practitioners (doctors, other healthcare professionals) | 1 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 101 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | <1% |
| Unknown | 100 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 18 | 18% |
| Student > Master | 14 | 14% |
| Other | 13 | 13% |
| Researcher | 7 | 7% |
| Student > Postgraduate | 7 | 7% |
| Other | 17 | 17% |
| Unknown | 25 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 31 | 31% |
| Pharmacology, Toxicology and Pharmaceutical Science | 11 | 11% |
| Nursing and Health Professions | 10 | 10% |
| Agricultural and Biological Sciences | 8 | 8% |
| Biochemistry, Genetics and Molecular Biology | 7 | 7% |
| Other | 8 | 8% |
| Unknown | 26 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2019.
All research outputs
#1,948,157
of 23,929,753 outputs
Outputs from Advances in Therapy
#161
of 2,435 outputs
Outputs of similar age
#40,519
of 426,441 outputs
Outputs of similar age from Advances in Therapy
#4
of 41 outputs
Altmetric has tracked 23,929,753 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,435 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 426,441 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.