| Title |
Behavioral Correlates of Maternal Antibody Status Among Children with Autism
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, October 2011
|
| DOI | 10.1007/s10803-011-1378-7 |
| Pubmed ID | |
| Authors |
Daniel Braunschweig, Paul Duncanson, Robert Boyce, Robin Hansen, Paul Ashwood, Isaac N. Pessah, Irva Hertz-Picciotto, Judy Van de Water |
| Abstract |
Autism spectrum disorders (ASDs) affect approximately 1 in 110 children in the United States. This report profiles fetal-brain reactive autoantibodies of a large cohort of mothers of children with autism and controls, yielding significant associations between the presence of IgG reactivity to fetal brain proteins at 37 and 73 kDa and a childhood diagnosis of full autism (p = 0.0005), which also correlated with lower expressive language scores (p = 0.005). Additionally, we report on reactivity to proteins at 39 and 73 kDa, which correlated with the broader diagnosis of ASD (p = 0.0007) and increased irritability on the Aberrant Behavioral Checklist (p = 0.05). This study provides evidence of multiple patterns of reactivity to fetal brain proteins by maternal antibodies associated with ASD and specific childhood behavioral outcomes. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 131 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 2% |
| Netherlands | 1 | <1% |
| Unknown | 127 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 22 | 17% |
| Student > Ph. D. Student | 21 | 16% |
| Student > Master | 15 | 11% |
| Student > Bachelor | 12 | 9% |
| Student > Doctoral Student | 10 | 8% |
| Other | 28 | 21% |
| Unknown | 23 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 24 | 18% |
| Agricultural and Biological Sciences | 23 | 18% |
| Psychology | 22 | 17% |
| Neuroscience | 12 | 9% |
| Biochemistry, Genetics and Molecular Biology | 8 | 6% |
| Other | 12 | 9% |
| Unknown | 30 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2023.
All research outputs
#3,148,806
of 25,177,382 outputs
Outputs from Journal of Autism and Developmental Disorders
#1,338
of 5,429 outputs
Outputs of similar age
#16,267
of 144,832 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#10
of 41 outputs
Altmetric has tracked 25,177,382 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,429 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 144,832 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.