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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Interferon‐γ: an overview of signals, mechanisms and functions
|
|---|---|
| Published in |
Journal of Leukocyte Biology, October 2003
|
| DOI | 10.1189/jlb.0603252 |
| Pubmed ID | |
| Authors |
Kate Schroder, Paul J. Hertzog, Timothy Ravasi, David A. Hume |
| Abstract |
Interferon-gamma (IFN-gamma) coordinates a diverse array of cellular programs through transcriptional regulation of immunologically relevant genes. This article reviews the current understanding of IFN-gamma ligand, receptor, signal transduction, and cellular effects with a focus on macrophage responses and to a lesser extent, responses from other cell types that influence macrophage function during infection. The current model for IFN-gamma signal transduction is discussed, as well as signal regulation and factors conferring signal specificity. Cellular effects of IFN-gamma are described, including up-regulation of pathogen recognition, antigen processing and presentation, the antiviral state, inhibition of cellular proliferation and effects on apoptosis, activation of microbicidal effector functions, immunomodulation, and leukocyte trafficking. In addition, integration of signaling and response with other cytokines and pathogen-associated molecular patterns, such as tumor necrosis factor-alpha, interleukin-4, type I IFNs, and lipopolysaccharide are discussed. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 50% |
| Germany | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 3,129 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 22 | <1% |
| Germany | 18 | <1% |
| United Kingdom | 18 | <1% |
| Spain | 5 | <1% |
| Belgium | 5 | <1% |
| Canada | 5 | <1% |
| Brazil | 5 | <1% |
| Netherlands | 4 | <1% |
| Australia | 3 | <1% |
| Other | 35 | 1% |
| Unknown | 3009 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 708 | 23% |
| Student > Master | 461 | 15% |
| Student > Bachelor | 451 | 14% |
| Researcher | 372 | 12% |
| Student > Doctoral Student | 197 | 6% |
| Other | 372 | 12% |
| Unknown | 568 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 912 | 29% |
| Biochemistry, Genetics and Molecular Biology | 479 | 15% |
| Medicine and Dentistry | 405 | 13% |
| Immunology and Microbiology | 358 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 59 | 2% |
| Other | 282 | 9% |
| Unknown | 634 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 32. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2023.
All research outputs
#1,268,691
of 25,837,817 outputs
Outputs from Journal of Leukocyte Biology
#81
of 4,312 outputs
Outputs of similar age
#1,265
of 57,390 outputs
Outputs of similar age from Journal of Leukocyte Biology
#1
of 35 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,312 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 57,390 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.