| Title |
Immunogenetic studies in autism and related disorders
|
|---|---|
| Published in |
Journal of Molecular Neuroscience, May 1996
|
| DOI | 10.1007/bf02815207 |
| Pubmed ID | |
| Authors |
R. P. Warren, V. K. Singh, R. E. Averett, J. D. Odell, A. Maciulis, R. A. Burger, W. W. Daniels, W. L. Warren |
| Abstract |
The major histocompatibility complex comprises a number of genes that control the function and regulation of the immune system. One of these genes, the C4B gene, encodes a product that is involved in eliminating pathogens such as viruses and bacteria from the body. We previously reported that a deficient form of the C4B gene, termed the C4B null allele (no C4B protein produced) had an increased frequently in autism. In this study we attempted to confirm the increased incidence of the C4B null allele in autism and investigated the presence of a C4B null allele in two other childhood disorders, attention-deficit hyperactivity disorder and dyslexia (reading disability). In addition, we explored the relationship of autism to the DR beta 1 gene, a gene located close to the C4B in autism. We confirmed the finding of an increased frequency of the C4B null allele in autism and found that the related disorders also had an increased frequency of this null allele. In addition, two alleles of the DR beta 1 gene also had significantly increased representation in the autistic subjects. |
Mendeley readers
The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Unknown | 42 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 19% |
| Student > Master | 6 | 14% |
| Student > Doctoral Student | 6 | 14% |
| Other | 5 | 12% |
| Student > Bachelor | 3 | 7% |
| Other | 11 | 26% |
| Unknown | 4 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 11 | 26% |
| Psychology | 6 | 14% |
| Agricultural and Biological Sciences | 6 | 14% |
| Neuroscience | 5 | 12% |
| Biochemistry, Genetics and Molecular Biology | 3 | 7% |
| Other | 2 | 5% |
| Unknown | 10 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 June 2018.
All research outputs
#3,274,230
of 25,374,917 outputs
Outputs from Journal of Molecular Neuroscience
#84
of 1,643 outputs
Outputs of similar age
#1,668
of 26,600 outputs
Outputs of similar age from Journal of Molecular Neuroscience
#1
of 10 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,643 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done particularly well, scoring higher than 94% of its peers.
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We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them