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Atlas of Gene Expression in the Developing Kidney at Microanatomic Resolution

Overview of attention for article published in Developmental Cell, November 2008
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

blogs
1 blog
patent
7 patents

Citations

dimensions_citation
196 Dimensions

Readers on

mendeley
152 Mendeley
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Title
Atlas of Gene Expression in the Developing Kidney at Microanatomic Resolution
Published in
Developmental Cell, November 2008
DOI 10.1016/j.devcel.2008.09.007
Pubmed ID
Authors

Eric W Brunskill, Bruce J Aronow, Kylie Georgas, Bree Rumballe, M Todd Valerius, Jeremy Aronow, Vivek Kaimal, Anil G Jegga, Jing Yu, Sean Grimmond, Andrew P McMahon, Larry T Patterson, Melissa H Little, S Steven Potter

Abstract

Kidney development is based on differential cell-type-specific expression of a vast number of genes. While multiple critical genes and pathways have been elucidated, a genome-wide analysis of gene expression within individual cellular and anatomic structures is lacking. Accomplishing this could provide significant new insights into fundamental developmental mechanisms such as mesenchymal-epithelial transition, inductive signaling, branching morphogenesis, and segmentation. We describe here a comprehensive gene expression atlas of the developing mouse kidney based on the isolation of each major compartment by either laser capture microdissection or fluorescence-activated cell sorting, followed by microarray profiling. The resulting data agree with known expression patterns and additional in situ hybridizations. This kidney atlas allows a comprehensive analysis of the progression of gene expression states during nephrogenesis, as well as discovery of potential growth factor-receptor interactions. In addition, the results provide deeper insight into the genetic regulatory mechanisms of kidney development.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 152 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 6 4%
India 2 1%
United Kingdom 1 <1%
Australia 1 <1%
Unknown 142 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 47 31%
Researcher 28 18%
Professor > Associate Professor 15 10%
Professor 13 9%
Student > Doctoral Student 7 5%
Other 20 13%
Unknown 22 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 62 41%
Biochemistry, Genetics and Molecular Biology 27 18%
Medicine and Dentistry 23 15%
Pharmacology, Toxicology and Pharmaceutical Science 3 2%
Business, Management and Accounting 2 1%
Other 11 7%
Unknown 24 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2023.
All research outputs
#2,475,113
of 25,374,917 outputs
Outputs from Developmental Cell
#1,173
of 4,318 outputs
Outputs of similar age
#7,379
of 105,270 outputs
Outputs of similar age from Developmental Cell
#2
of 26 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,318 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.0. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 105,270 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.