| Title |
The CARD8 p.C10X mutation associates with a low anti-glycans antibody response in patients with Crohn’s disease
|
|---|---|
| Published in |
BMC Medical Genomics, March 2013
|
| DOI | 10.1186/1471-2350-14-35 |
| Pubmed ID | |
| Authors |
Francis Vasseur, Boualem Sendid, Franck Broly, Corinne Gower-Rousseau, Aurore Sarazin, Annie Standaert-Vitse, Jean-Frederic Colombel, Daniel Poulain, Thierry Jouault |
| Abstract |
Crohn's disease (CD) is associated with elevated anti-glycans antibody response in 60% of CD patients, and 25% of healthy first-degree relatives (HFDRs), suggesting a genetic influence for this humoral response. In mice, anti-glucan antibody response depends on the NLRP3 inflammasome. Here, we explored the effect of mutated CARD8, a component of the inflammasome, on anti-glycans antibody response in human. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 10 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 2 | 20% |
| Researcher | 2 | 20% |
| Professor | 1 | 10% |
| Librarian | 1 | 10% |
| Other | 1 | 10% |
| Other | 1 | 10% |
| Unknown | 2 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 2 | 20% |
| Agricultural and Biological Sciences | 2 | 20% |
| Immunology and Microbiology | 2 | 20% |
| Biochemistry, Genetics and Molecular Biology | 1 | 10% |
| Computer Science | 1 | 10% |
| Other | 0 | 0% |
| Unknown | 2 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 May 2013.
All research outputs
#16,721,208
of 25,373,627 outputs
Outputs from BMC Medical Genomics
#1,194
of 2,444 outputs
Outputs of similar age
#138,053
of 222,519 outputs
Outputs of similar age from BMC Medical Genomics
#11
of 18 outputs
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So far Altmetric has tracked 2,444 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
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