| Title |
Viral–Bacterial Interactions in Acute Otitis Media
|
|---|---|
| Published in |
Current Allergy and Asthma Reports, September 2012
|
| DOI | 10.1007/s11882-012-0303-2 |
| Pubmed ID | |
| Authors |
Tal Marom, Johanna Nokso-Koivisto, Tasnee Chonmaitree |
| Abstract |
Acute otitis media (AOM) is a polymicrobial disease, which usually occurs as a complication of viral upper respiratory tract infection (URI). While respiratory viruses alone may cause viral AOM, they increase the risk of bacterial middle ear infection and worsen clinical outcomes of bacterial AOM. URI viruses alter Eustachian tube (ET) function via decreased mucociliary action, altered mucus secretion and increased expression of inflammatory mediators among other mechanisms. Transient reduction in protective functions of the ET allows colonizing bacteria of the nasopharynx to ascend into the middle ear and cause AOM. Advances in research help us to better understand the host responses to viral URI, the mechanisms of viral-bacterial interactions in the nasopharynx and the development of AOM. In this review, we present current knowledge regarding viral-bacterial interactions in the pathogenesis and clinical course of AOM. We focus on the common respiratory viruses and their established role in AOM. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | 1% |
| Chile | 1 | 1% |
| Portugal | 1 | 1% |
| Canada | 1 | 1% |
| Unknown | 91 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 11 | 12% |
| Researcher | 10 | 11% |
| Student > Master | 10 | 11% |
| Student > Bachelor | 9 | 9% |
| Professor > Associate Professor | 6 | 6% |
| Other | 22 | 23% |
| Unknown | 27 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 35 | 37% |
| Immunology and Microbiology | 10 | 11% |
| Agricultural and Biological Sciences | 9 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 3% |
| Nursing and Health Professions | 2 | 2% |
| Other | 8 | 8% |
| Unknown | 28 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 May 2013.
All research outputs
#18,339,860
of 22,711,242 outputs
Outputs from Current Allergy and Asthma Reports
#653
of 803 outputs
Outputs of similar age
#128,360
of 168,592 outputs
Outputs of similar age from Current Allergy and Asthma Reports
#22
of 27 outputs
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