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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Impact of coronary heart disease on cognitive decline in Alzheimer’s disease: a prospective longitudinal cohort study in primary care
|
|---|---|
| Published in |
British Journal of General Practice, December 2016
|
| DOI | 10.3399/bjgp16x688813 |
| Pubmed ID | |
| Authors |
Markus Bleckwenn, Luca Kleineidam, Michael Wagner, Frank Jessen, Siegfried Weyerer, Jochen Werle, Birgitt Wiese, Dagmar Lühmann, Tina Posselt, Hans-Helmut König, Christian Brettschneider, Edelgard Mösch, Dagmar Weeg, Angela Fuchs, Michael Pentzek, Tobias Luck, Steffi G Riedel-Heller, Wolfgang Maier, Martin Scherer |
| Abstract |
Arteriosclerotic disorders increase the risk of dementia. As they have common causes and risk factors, coronary heart disease (CHD) could influence the course of dementia. To determine whether CHD increases the speed of cognitive decline in Alzheimer's disease, and to discuss the potential for secondary cardiovascular prevention to modify this decline. Prospective multicentre cohort study in general practices in six cities in Germany. Participants were patients with probable mild-to-moderate Alzheimer's dementia or mixed dementia (n = 118; mean age 85.6 [±3.4] years, range 80-96 years). The authors assessed the presence of CHD according to the family physicians' diagnosis. Cognitive performance was measured during home visits for up to 3 years in intervals of 6 months, using Mini Mental State Examination (MMSE) and Clinical Dementia Rating Sum of Boxes (CDR-SoB). The authors also recorded whether patients died in the observation period. At baseline, 65 patients (55%) had CHD and/or a heart condition following a myocardial infarction. The presence of CHD accelerated cognitive decline (MMSE, P<0.05) by about 66%, and reduced cognitive-functional ability (CDR-SoB, P<0.05) by about 83%, but had no impact on survival. The study shows that CHD has a significant influence on cognitive decline in older patients with late-onset dementia. The dementia process might therefore be positively influenced by cardiovascular prevention, and this possible effect should be further investigated. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 4 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 1% |
| Unknown | 94 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 16 | 17% |
| Researcher | 11 | 12% |
| Student > Master | 11 | 12% |
| Student > Ph. D. Student | 8 | 8% |
| Other | 6 | 6% |
| Other | 12 | 13% |
| Unknown | 31 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 23% |
| Nursing and Health Professions | 14 | 15% |
| Psychology | 8 | 8% |
| Neuroscience | 4 | 4% |
| Materials Science | 2 | 2% |
| Other | 6 | 6% |
| Unknown | 39 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 March 2017.
All research outputs
#2,640,525
of 23,321,213 outputs
Outputs from British Journal of General Practice
#1,217
of 4,354 outputs
Outputs of similar age
#54,403
of 422,779 outputs
Outputs of similar age from British Journal of General Practice
#25
of 84 outputs
Altmetric has tracked 23,321,213 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,354 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 19.2. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 422,779 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.