| Title |
Efficacy of anti-staphylococcal protein P128 for the treatment of canine pyoderma: potential applications
|
|---|---|
| Published in |
Veterinary Research Communications, May 2013
|
| DOI | 10.1007/s11259-013-9565-y |
| Pubmed ID | |
| Authors |
Raghu Patil Junjappa, Srividya Narayanamurthy Desai, Panchali Roy, Nagalakshmi Narasimhaswamy, Juliet Roshini Mohan Raj, Murali Durgaiah, Aradhana Vipra, Udaya Ravi Bhat, Smitha Komarla Satyanarayana, Nandini Shankara, SuneelKumar Muragesh Basingi, Jagadeesh Janardhan Bhat, Sukumar Hariharan, Bharathi Sriram, Sriram Padmanabhan |
| Abstract |
In this study, we demonstrate the antibacterial activity of P128 on Staphylococcus isolates responsible for canine pyoderma. Eighty seven swabs were collected from dogs suffering from pyoderma and subjected to antibiotic sensitivity test and 46 Staphylococcus strains were isolated and characterized. In-vitro antimicrobial susceptibility testing with P128 was done by Minimum Inhibitory Concentration (MIC) method as per CLSI guidelines. All the Staphylococci isolated from the dogs with pyoderma, although showed resistance to various antibiotics tested, were lysed by P128. Clinical efficacy of P128 was examined in 17 dogs with pyoderma by application of the P128 hydrogel twice daily for 8 days and the results indicated complete healing of all the lesions of all the dogs under treatment. Under the conditions of this study, P128 was found to be a potent convenient proteinaceous drug for the treatment of staphylococcal pyoderma in dogs. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Argentina | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sri Lanka | 1 | 3% |
| Unknown | 35 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 22% |
| Researcher | 5 | 14% |
| Student > Postgraduate | 3 | 8% |
| Student > Bachelor | 2 | 6% |
| Professor > Associate Professor | 2 | 6% |
| Other | 5 | 14% |
| Unknown | 11 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 10 | 28% |
| Agricultural and Biological Sciences | 6 | 17% |
| Immunology and Microbiology | 3 | 8% |
| Medicine and Dentistry | 2 | 6% |
| Veterinary Science and Veterinary Medicine | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 13 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 May 2020.
All research outputs
#6,392,410
of 22,711,242 outputs
Outputs from Veterinary Research Communications
#67
of 468 outputs
Outputs of similar age
#53,981
of 193,513 outputs
Outputs of similar age from Veterinary Research Communications
#1
of 2 outputs
Altmetric has tracked 22,711,242 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 468 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 193,513 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them